Results 51 to 60 of about 1,174,696 (280)

Real‐World Performance of CSF Kappa Free Light Chains in the 2024 McDonald Criteria

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Kappa free light chains (KFLCs) in the cerebrospinal fluid (CSF) have a similar performance to CSF‐restricted oligoclonal bands (OCB) for multiple sclerosis (MS) diagnosis. To help with implementation, we set out to resolve several remaining uncertainties: (1) performance in a real‐world cohort and the 2024 McDonald criteria; (2 ...
Maya M. Leibowitz, Ryan Cooper, Stefania Kaninia, Kathryn I. Challis, Will Greenway, Maria Bonello, Mahmoud Elbahnasawi, Deborah T. Shode, Dominika Gajdasik, Victor Iliev, Alison M. E. Whitelegg, Ian Galea   +11 more
wiley   +1 more source

Determination of Significant Parameters on the Basis of Methods of Mathematical Statistics, and Boolean and Fuzzy Logic

Mathematics, 2022
Among the set of parameters for which data are collected for decision-making based on artificial intelligence methods, often only some of the parameters are significant.
Yulia Shichkina, Mikhail Petrov, Fatkieva Roza   +2 more
doaj   +1 more source

Discussion of "EQUI-energy sampler" by Kou, Zhou and Wong

, 2006
Discussion of ``EQUI-energy sampler'' by Kou, Zhou and Wong [math.ST/0507080]Comment: Published at http://dx.doi.org/10.1214/009053606000000506 in the Annals of Statistics (http://www.imstat.org/aos/) by the Institute of Mathematical Statistics (http:
Wu, Ying Nian, Zhu, Song-Chun
core   +1 more source

Association of CDKN2A/B Homozygous Deletion and Extent of Resection With Survival of Patients With WHO CNS5 Grade 4 Astrocytoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives WHO grade 4 astrocytomas are associated with poor prognosis, and their prognostic factors remain controversial. This study aimed to identify the prognostic factors and develop a management algorithm for these patients. Methods This study retrospectively included 151 CNS5 adult grade 4 astrocytomas from two medical centers.
Jiawei Cai, Guanglin Zhu, Qiu He, Chen Luo, Lingyun Zhuo, Xingfu Wang, Yiming Chen, Xiaoyong Chen, Wendong You, Jiaheng Xu, Yuanxiang Lin, Dezhi Kang, Shuai Wu, Zanyi Wu   +13 more
wiley   +1 more source

Rejoinder to discussions of "Frequentist coverage of adaptive nonparametric Bayesian credible sets" [PDF]

, 2015
Rejoinder of "Frequentist coverage of adaptive nonparametric Bayesian credible sets" by Szab\'o, van der Vaart and van Zanten [arXiv:1310.4489v5].Comment: Published at http://dx.doi.org/10.1214/15-AOS1270REJ in the Annals of Statistics (http://www ...
Szabó, Botond, van der Vaart, A. W., van Zanten, J. H.   +2 more
core   +6 more sources

Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang, Brian S. Gloss, Jessica P. Hayes, Andrew J. A. Holland, Manoj P. Menezes, Joceline A. Branson, Shekeeb S. Mohammad, Jingya J. Yan, Shrujna Patel, Velda X. Han, Russell C. Dale   +10 more
wiley   +1 more source

Statistical Analysis of Inverse Weibull based on Step-Stress Partially Accelerated Life Tests with Unified Hybrid Censoring Data

Computational Journal of Mathematical and Statistical Sciences
Accelerated life testing (ALT) is a primary method for rapidly evaluating product reliability. This paper focuses on statistical inference for the invertedWeibull distribution under a step-stress partially ALT (SSPALT) model with a unified hybrid ...
Amal Soliman Hassan, Abd ELwahab Hagag, Nader Metwally, Omar Hussein Sery   +3 more
doaj   +1 more source

Development of a comprehensive methodology for the forecast of effectiveness of geological and technical measures based on machine learning algorithms

Georesursy, 2020
The main part of hydrocarbon production in Russia is represented by old oil and gas producing regions. Such areas are characterized by a significant decrease in well productivity due to high water cut and faster production of the most productive ...
Alexander A. Kochnev, Nikita D. Kozyrev , Olga E. Kochneva , Sergey V. Galkin   +3 more
doaj   +1 more source

Discussion: Latent variable graphical model selection via convex optimization

, 2012
Discussion of "Latent variable graphical model selection via convex optimization" by Venkat Chandrasekaran, Pablo A. Parrilo and Alan S. Willsky [arXiv:1008.1290].Comment: Published in at http://dx.doi.org/10.1214/12-AOS984 the Annals of Statistics ...
Giraud, Christophe, Tsybakov, Alexandre
core   +1 more source

Quantifying the Impact of Ocrelizumab on Paramagnetic Rim Lesions in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Paramagnetic rim lesions (PRLs) are a subset of chronic active multiple sclerosis (MS) lesions marked by iron‐laden microglia and macrophages. Ocrelizumab, a monoclonal antibody targeting CD20+ B cells, suppresses acute MS activity, but its effect on PRLs remains unclear. In a longitudinal study of 29 ocrelizumab‐treated patients with at least
Kimberly H. Markowitz, Neha V. Safi, Iliana Pliska‐Bloch, Ulrike W. Kaunzner, Ha Luu, Mert Sisman, Yi Wang, Thanh D. Nguyen, Sandra Hurtado Rúa, Susan A. Gauthier   +9 more
wiley   +1 more source