Results 21 to 30 of about 672,804 (238)
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Topical Bias in Generalist Mathematics Journals [PDF]
, 2010 Generalist mathematics journals exhibit bias toward the branches of mathematics by publishing articles about some subjects in quantities far disproportionate to the production of papers in those areas within all of mathematics.Comment: 8 pages, 3 ...
Grcar, Joseph F.
core
FEBS Open Bio, EarlyView.Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
Finance and Market, 2016 <p><span style="font-family: Times New Roman; font-size: medium;">The random complex variable is a kind of random variable which in complex number as the random variable. In this paper, study on mathematical conjecture of random complex variable, two-dimensional joint distribution and complex expected, complex variance and other common ...
openaire +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
, 2015 A.M. Mathai is Emeritus Professor of Mathematics and Statistics at McGill University, Canada, and Director of the Centre for Mathematical and Statistical Sciences, India.
Haubold, H. J., Mathai, A. M.
core +2 more sources
Real‐World Performance of CSF Kappa Free Light Chains in the 2024 McDonald Criteria
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Kappa free light chains (KFLCs) in the cerebrospinal fluid (CSF) have a similar performance to CSF‐restricted oligoclonal bands (OCB) for multiple sclerosis (MS) diagnosis. To help with implementation, we set out to resolve several remaining uncertainties: (1) performance in a real‐world cohort and the 2024 McDonald criteria; (2 ...
Maya M. Leibowitz +11 more
wiley +1 more source
Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang +10 more
wiley +1 more source
Iterated socles and integral dependence in regular rings [PDF]
, 2014 Let $R$ be a formal power series ring over a field, with maximal ideal $\mathfrak m$, and let $I$ be an ideal of $R$ such that $R/I$ is Artinian. We study the iterated socles of $I$, that is the ideals which are defined as the largest ideal $J$ with $J ...
Corso, Alberto +4 more
core
Upper-division student difficulties with Separation of Variables
, 2015 Separation of variables can be a powerful technique for solving many of the partial differential equations that arise in physics contexts. Upper-division physics students encounter this technique in multiple topical areas including electrostatics and ...
Pollock, Steven J., Wilcox, Bethany R.
core +2 more sources