Results 21 to 30 of about 1,847,581 (285)
Persistence and Permanence of Mass-Action and Power-Law Dynamical Systems [PDF]
SIAM Journal on Applied Mathematics, 2010 Persistence and permanence are properties of dynamical systems that describe the long-term behavior of the solutions and in particular specify whether positive solutions approach the boundary of the positive orthant.
G. Craciun, F. Nazarov, Casian Pantea
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A Study of Chaos in Dynamical Systems
, 2018 The behavior of systems such as periodicity, fixed points, and most importantly chaos has evolved as an integral part of mathematics, especially in dynamical system. This research presents a study on chaos as a property of nonlinear science. Systems with
S. Effah-Poku +2 more
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Parallel Dynamical Systems over Graphs and Related Topics: A Survey
Journal of Applied Mathematics, 2015 In discrete processes, as computational or genetic ones, there are many entities and each entity has a state at a given time. The update of states of the entities constitutes an evolution in time of the system, that is, a discrete dynamical system ...
J. Aledo, S. M. Sanahuja, J. Valverde
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FEBS Letters, EarlyView.In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker +8 more
wiley +1 more source
Molecular Oncology, EarlyView.This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu +12 more
wiley +1 more source
Decrypting cancer's spatial code: from single cells to tissue niches
Molecular Oncology, EarlyView.Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik +4 more
wiley +1 more source
Understanding and measuring mechanical signals in the tumor stroma
FEBS Open Bio, EarlyView.This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi +2 more
wiley +1 more source
CD9‐association with PIP2 areas is regulated by a CD9 salt bridge
FEBS Open Bio, EarlyView.The tetraspanin CD9 has an intracellular salt bridge. If CD9 opens, open‐CD9 moves from PIP2‐rich areas to regions populated by its interaction partner EWI‐2. Hence, the state of the salt bridge regulates the distribution of CD9 and by this CD9‐EWI‐2 complex formation.
Yahya Homsi +2 more
wiley +1 more source
Discussion: “A Method for Reducing the Number of Degrees of Freedom in Mathematical Models of Damped Linear Dynamic Systems” (Staffeld, S. E., 1962, ASME J. Eng. Ind., 84, pp. 418–421) [PDF]
, 1962 E. H. Stepp
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