Results 21 to 30 of about 21,395 (266)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

SUBSTITUTIONS, TILING DYNAMICAL SYSTEMS AND MINIMAL SELF-JOININGS

open access: yes, 2014
We investigate substitution subshifts and tiling dynamical systems arising from the substitutions (1) theta : 0 -> 001, 1 -> 11001 and (2) eta : 0 > 001, 1 -> 11100. We show that the substitution subshifts arising from 61 and n have minimal self-joinings
Son, Younghwan
core   +1 more source

Time-Dependent Dynamical Systems and Geophysical Flows [PDF]

open access: yes, 2003
This thesis presents a dynamical systems approach to transport and mixing in geophysical flows. First, new algorithms are developed that allow one to study a dynamical system that is described in a variety of ways such as by means of observational data ...
Lekien, Francois Paul
core   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

Vibration, Control and Stability of Dynamical Systems [PDF]

open access: yes, 2017
From Preface: This is the fourteenth time when the conference “Dynamical Systems: Theory and Applications” gathers a numerous group of outstanding scientists and engineers, who deal with widely understood problems of theoretical and applied dynamics ...

core   +1 more source

MATHEMATICAL MODELING OF BEHÇET'S DISEASE: A DYNAMICAL SYSTEMS APPROACH

open access: yesJournal of Biological Systems, 2015
Behçet's Disease (BD) is a multi-systemic, auto-inflammatory disorder that is characterized by recurrent episodes of inflammatory manifestations affecting skin, mucosa, eyes, blood vessels, joints and several other organs. BD is classified as a multifactorial disease with an important contribution of genetics.
ERDEM C   +4 more
openaire   +3 more sources

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Standalone DC microgrids as complementarity dynamical systems: Modeling and applications [PDF]

open access: yes, 2015
It is well known that, due to bimodal operation as well as existent discontinuous differential states of batteries, standalone microgrids belong to the class of hybrid dynamical systems of non-Filippov type.
Alireza Maheri (16272944)   +11 more
core   +1 more source

Aspects of Poincaré’s Program for Dynamical Systems and Mathematical Physics [PDF]

open access: yesActa Applicandae Mathematicae, 2012
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +2 more sources

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