Results 31 to 40 of about 1,914 (167)

Talking as friends: Weaving local and scientific knowledge to co‐produce an integrated index to assess rangeland multifunctionality in a dryland Biosphere Reserve in Mexico

People and Nature, EarlyView.
Abstract The complexity of sustainability challenges and the need for transformative change have prompted the exploration of novel approaches for knowledge co‐generation and decision‐making. This calls for integrative assessment methods that meaningfully include and represent diverse knowledge systems, capturing multiple values, needs and interests as ...
Ricardo Ismael Mata‐Páez, Elisabeth Huber‐Sannwald, Natalia Martínez‐Tagüeña, Ruperto Cázares‐Reyes, Víctor Manuel Reyes‐Gómez, Juan José López‐Pardo, Sandra Hernández‐Valdez   +6 more
wiley   +1 more source

Mining Alzheimer's Interactomes, Macromolecular Complexes and Pathways for Drug Discovery

PROTEOMICS, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a progressive neurodegenerative disorder that leads to dementia. Many cases are diagnosed annually and there is no currently available cure. Understanding the underlying disease biology of AD through the study of molecular networks, particularly by mapping clinical variants to tissue‐specific interactomes and ...
Kalpana Panneerselvam, Krishna Kumar Tiwari, Luana Licata, Simona Panni, Sylvie Ricard‐Blum, Sucharitha Balu, Susie Huget, Juan Jose Medina Reyes, Eliot Ragueneau, Livia Perfetto, Birgit Meldal, Sandra Orchard, Henning Hermjakob   +12 more
wiley   +1 more source

Structure Modeling Protocols for Protein Multimer and RNA in CASP16 With Enhanced MSAs, Model Ranking, and Deep Learning

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT We present the methods and results of our protein complex and RNA structure predictions at CASP16. Our approach integrated multiple state‐of‐the‐art deep learning models with a consensus‐based scoring method. To enhance the depth of multiple sequence alignments (MSAs), we employed a large metagenomic sequence database.
Yuki Kagaya, Tsukasa Nakamura, Jacob Verburgt, Anika Jain, Genki Terashi, Pranav Punuru, Emilia Tugolukova, Joon Hong Park, Anouka Saha, David Huang, Daisuke Kihara   +10 more
wiley   +1 more source

Characteristic Curves for Multiple‐Inspector Sampling Plans with Inspection Errors

Quality and Reliability Engineering International, EarlyView.
ABSTRACT Classical single sampling plans (SSPs) are designed assuming that product units sampled from a lot are inspected by one inspector, in the absence or presence of inspection errors. The scenario becomes more complicated when SSPs are applied assuming that multiple inspectors operate in parallel on the same sample, as occasionally required in ...
Domenico A. Maisano, Lucrezia Ferrara, Fiorenzo Franceschini   +2 more
wiley   +1 more source

Toward Useful Quantum Kernels

Advanced Quantum Technologies, EarlyView.
The hybrid approach to Quantum Supervised Machine Learning is compatible with Noisy Intermediate Scale Quantum (NISQ) devices but hardly useful. Pure quantum kernels requiring fault‐tolerant quantum computers are more promising. Examples are kernels computed by means of the Quantum Fourier Transform (QFT) and kernels defined via the calculation of ...
Massimiliano Incudini, Francesco Martini, Alessandra Di Pierro   +2 more
wiley   +1 more source

GAN Decoder on a Quantum Toric Code for Noise‐Robust Quantum Teleportation

Advanced Quantum Technologies, EarlyView.
This study proposes a novel quantum topological code decoder using generative adversarial networks (GANs). By training the GAN with eigenvalue datasets, an enhanced decoding threshold and robust quantum teleportation under depolarizing noise are achieved.
Jiaxin Li, Zhimin Wang, Alberto Ferrara, Yongjian Gu, Rosario Lo Franco   +4 more
wiley   +1 more source

Kinetic Mechanism of Substoichiometric Inhibition of Huntingtin Exon‐1 Protein Aggregation by Selenium Nanoparticles

Small Science, EarlyView.
Using a combination of NMR spectroscopy, fluorescence immunostaining, and electron microscopy, it is shown that selenium nanoparticles reduce the rate of huntingtin exon‐1 protein fibril formation, substoichiometrically with respect to monomer, by targeting and binding with nanomolar affinity to the extendable ends of elongation‐competent species ...
Francesco Torricella, Vitali Tugarinov, G. Marius Clore   +2 more
wiley   +1 more source

A topological exploration of convergence/divergence of human‐mediated and algorithmically mediated pedagogy

British Journal of Educational Technology, EarlyView.
We explore a topological model that situates teachers' agency as a constituent element within the convergent and divergent dynamics at the intersection of human‐mediated and algorithmically mediated pedagogies. Ubiquitous AI in education is designed to simulate, emulate and automate human processes and behaviours through datafication.
Keith Turvey, Norbert Pachler
wiley   +1 more source

The Nature of Christian Doctrine: A Conversation with My Critics

International Journal of Systematic Theology, EarlyView.
Abstract This article opens with a brief account of the six main themes of The Nature of Christian Doctrine, noting in particular the role of the early church as an ‘epistemic community’ of knowledge production, and the significant and helpful parallels between the modern scientific tool of ‘inference to the best explanation’ and early Christian ...
Alister E. McGrath
wiley   +1 more source

A suture in time: The ontogeny of cranial suture morphology in mammals

Journal of Anatomy, EarlyView.
Mammal cranial sutures are important indicators of the biomechanical and developmental pressures acting upon the skull. Across three prominent sutures dividing the vault of the mammalian skull, divergent patterns emerge both taxonomically and developmentally.
Heather E. White, Marco Camaiti, Abigail S. Tucker, Akinobu Watanabe, Anjali Goswami   +4 more
wiley   +1 more source