Results 31 to 40 of about 1,848 (135)

Circumventing glioblastoma resistance to temozolomide through optimal drug combinations designed by systems pharmacology and machine learning

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Glioblastoma (GBM), the most frequent and aggressive brain tumour in adults, is associated with a dismal prognostic despite intensive treatment involving surgery, radiotherapy and temozolomide (TMZ)‐based chemotherapy. The initial or acquired resistance of GBM to TMZ appeals for precision medicine approaches to the design of ...
Sergio Corridore   +6 more
wiley   +1 more source

State‐of‐the‐art Report in Sketch Processing

open access: yesComputer Graphics Forum, EarlyView.
Abstract Sketches are a powerful and natural form of communication and are used in numerous systems for modelling, animation, shape retrieval, and editing. Despite their popularity, rough sketches — whether raster or vector, 2D or 3D — are often too complex and imprecise to be used directly and thus need special processing.
Chenxi Liu, Mikhail Bessmeltsev
wiley   +1 more source

When Dimensionality Reduction Meets Graph (Drawing) Theory: Introducing a Common Framework, Challenges and Opportunities

open access: yesComputer Graphics Forum, EarlyView.
Abstract In the vast landscape of visualization research, Dimensionality Reduction (DR) and graph analysis are two popular subfields, often essential to most visual data analytics setups. DR aims to create representations to support neighborhood and similarity analysis on complex, large datasets.
F. V. Paulovich   +2 more
wiley   +1 more source

Establishing new grid‐size‐dependent attributes to rank areas of endemism for conservation priorities

open access: yesCladistics, EarlyView.
Abstract Delineating Areas of Endemism (AEs) is crucial for identifying priority areas for biodiversity conservation in a spatial planning framework. Endemicity Analysis in the NDM/VNDM software is one of the primary methodologies for its delineation.
Augusto Frota, Weferson Júnio da Graça
wiley   +1 more source

Modeling and Analyzing Urban Networks and Amenities With OSMnx

open access: yesGeographical Analysis, EarlyView.
ABSTRACT OSMnx is a Python package for downloading, modeling, analyzing, and visualizing urban networks and any other geospatial features from OpenStreetMap data. A large and growing body of literature uses it to conduct scientific studies across the disciplines of geography, urban planning, transport engineering, computer science, and others.
Geoff Boeing
wiley   +1 more source

Topological Data Analysis Based Characteristics of Electroencephalogram Signals in Children With Sleep Apnea

open access: yesJournal of Sleep Research, EarlyView.
ABSTRACT This study aims to identify differences in the functional neural connectivity of the brain of paediatric patients with obstructive sleep apnea. Using EEG signals from 3673 paediatric patients, we grouped subjects into OSA or control groups based on sleep oxygen desaturation levels and apnea‐hypopnea index (AHI), and applied topological data ...
Aarti Sathyanarayana   +2 more
wiley   +1 more source

The Facilitator Problem: Politicizing Epistemic‐Democratic Assumptions in the People's Republic of China

open access: yesPhilosophy &Public Affairs, EarlyView.
ABSTRACT Within discussions of deliberative democracy, the role of facilitator is ever‐present: they gather participants, introduce expert information, correct for discursive prejudices, and more. Few recognize, however, that facilitators therefore exercise substantive, normative control over the process, thereby constituting a threat to the legitimacy
Emerson R. Bodde
wiley   +1 more source

On the injective dimension of unit Cartier and unit Frobenius modules

open access: yesBulletin of the London Mathematical Society, EarlyView.
Abstract Let R$R$ be a regular F$F$‐finite ring of prime characteristic p$p$. We prove that the injective dimension of every unit Frobenius module M$M$ in the category of unit Frobenius modules is at most dim(SuppR(M))+1$\dim (\operatorname{Supp}_R(M))+1$.
Manuel Blickle   +3 more
wiley   +1 more source

Noncompact surfaces, triangulations and rigidity

open access: yesBulletin of the London Mathematical Society, EarlyView.
Abstract Every noncompact surface is shown to have a (3,6)‐tight triangulation, and applications are given to the generic rigidity of countable bar‐joint frameworks in R3${\mathbb {R}}^3$. In particular, every noncompact surface has a (3,6)‐tight triangulation that is minimally 3‐rigid. A simplification of Richards' proof of Kerékjártó's classification
Stephen C. Power
wiley   +1 more source

Presentation of kernels of rational characters of right‐angled Artin groups

open access: yesBulletin of the London Mathematical Society, EarlyView.
Abstract In this note, we characterise when the kernel of a rational character of a right‐angled Artin group, also known as generalised Bestiva–Brady group, is finitely generated and finitely presented. In these cases, we exhibit a finite generating set and a presentation.
Montserrat Casals‐Ruiz   +2 more
wiley   +1 more source

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