Results 31 to 40 of about 61,144 (126)

Living Microbial Drugs

open access: yesChemistry – A European Journal, EarlyView.
The introduction outlines the review scope. Microbial cell factories as living drugs cover host–gut microbiota, bacteria, yeast, and other microbial systems, with comparative host advantages. Engineering strategies include synthetic circuits, quorum sensing, and memory.
Cemile Elif Özçelik   +3 more
wiley   +1 more source

Ovarian Cancer: Epidemiology, Disease Mechanisms, New Diagnosis and Treatment Strategies, and Research Directions

open access: yesiNew Medicine, EarlyView.
ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid   +4 more
wiley   +1 more source

Speciation with gene flow

open access: yesPLANTS, PEOPLE, PLANET, EarlyView.
Biodiversity is threatened by human activities, with extinction debt accumulating rapidly. Many of these activities change the connectivity of populations, fragmenting existing population systems or bringing previously isolated populations or species into contact.
Zhiqin Long   +7 more
wiley   +1 more source

The X‐Ray Crystal Structure of BorF, the Flavin Reductase Subunit of a Two‐Component Flavin‐Dependent Tryptophan Halogenase

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT BorF is a short‐chain flavin reductase from a desert soil bacterium that uses NADH to reduce FAD to FADH2, which is used by the tryptophan‐6‐halogenase BorH to chlorinate tryptophan in the biosynthetic pathway of borregomycin A. The X‐ray crystal structure of BorF bound to FAD was solved to 2.37 Å by molecular replacement.
Zheng Ma   +3 more
wiley   +1 more source

Investigating the Environmental Impact of Additive Construction: A Systematic Analysis of the Life Cycle Assessment Studies

open access: yesSustainable Development, EarlyView.
ABSTRACT Additive Manufacturing (AM) has been identified as a potential catalyst for a paradigm shift within the construction industry, due to its capacity to enhance sustainability, reduce waste, and augment design flexibility. This study presents a systematic literature review (SLR) that explores the application of Life Cycle Assessment (LCA) in ...
Antonio Mastropasqua   +3 more
wiley   +1 more source

Information Dynamics and Learning in Complex Adaptive Systems: Toward a Transdisciplinary Framework

open access: yesSystems Research and Behavioral Science, EarlyView.
ABSTRACT This article develops a framework for understanding learning and adaptation in complex adaptive systems. Drawing from neuroscience, systems theory, information theory and quantum field theory, it examines how information processing, plasticity and systemic coherence emerge from distributed, nonlinear and feedback‐driven interactions. It argues
Anderson de Souza Sant'Anna
wiley   +1 more source

Non‐Rigid 3D Shape Correspondences: From Foundations to Open Challenges and Opportunities

open access: yesComputer Graphics Forum, EarlyView.
Abstract Estimating correspondences between deformed shape instances is a long‐standing problem in computer graphics; numerous applications, from texture transfer to statistical modelling, rely on recovering an accurate correspondence map. Many methods have thus been proposed to tackle this challenging problem from varying perspectives, depending on ...
A. Zhuravlev   +14 more
wiley   +1 more source

The Nature of Christian Doctrine: A Conversation with My Critics

open access: yesInternational Journal of Systematic Theology, EarlyView.
Abstract This article opens with a brief account of the six main themes of The Nature of Christian Doctrine, noting in particular the role of the early church as an ‘epistemic community’ of knowledge production, and the significant and helpful parallels between the modern scientific tool of ‘inference to the best explanation’ and early Christian ...
Alister E. McGrath
wiley   +1 more source

Fish welfare in a changing world: New developments and current challenges

open access: yesJournal of Fish Biology, EarlyView.
Abstract The welfare of non‐human animals is central to ethical discussions on animal use, with increasing attention to fish welfare across research, aquaria, aquaculture, and fisheries. This paper reviews current theoretical approaches to animal welfare and recent advances in defining and assessing fish welfare since the seminal paper by Huntingford ...
Sonia Rey Planellas   +16 more
wiley   +1 more source

Adenine nucleotide translocator and ATP synthase cooperate in mediating the mitochondrial permeability transition

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Both ATP synthase and adenine nucleotide translocator (ANT) play key roles in mediating the permeability transition. The contribution of ANT becomes evident in the presence of atractylate (ATR) at pH 6.5, a condition that prevents ATP synthase channel activity. At pH 7.4, this effect is minimal, suggesting a critical role for ATP
Ludovica Tommasin   +7 more
wiley   +1 more source

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