Results 51 to 60 of about 1,914 (167)

A note on the cohomology of moduli spaces of local shtukas

open access: yesBulletin of the London Mathematical Society, EarlyView.
Abstract We study localized versions of spectral action of Fargues–Scholze, using methods from higher algebra. As our main motivation and application, we deduce a formula for the cohomology of moduli spaces of local shtukas under certain genericity assumptions, and discuss its relation with the Kottwitz conjecture.
David Hansen, Christian Johansson
wiley   +1 more source

Residually rationally solvable one‐relator groups

open access: yesBulletin of the London Mathematical Society, EarlyView.
Abstract We show that the intersection of the rational derived series of a one‐relator group is rationally perfect and is normally generated by a single element. As a corollary, we characterise precisely when a one‐relator group is residually rationally solvable.
Marco Linton
wiley   +1 more source

Simple groups with strong fixed‐point properties

open access: yesBulletin of the London Mathematical Society, EarlyView.
Abstract We exhibit finitely generated torsion‐free groups for which any action on any finite‐dimensional CW‐complex with finite Betti numbers has a global fixed point.
Nansen Petrosyan
wiley   +1 more source

Intersectin‐1 enhances calcium‐dependent replenishment of the readily releasable pool of synaptic vesicles during development

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend During development, Intersectin‐1 (Itsn1) translocates near voltage‐gated calcium channels (VGCCs) to enhance Ca2+‐dependent replenishment of readily releasable synaptic vesicles (SVs). In the presynaptic terminal, SVs undergo a cycle involving formation (step 1), docking (step 2), exocytosis (step 3), endocytosis (step 4) and ...
Yi‐Mei Yang   +13 more
wiley   +1 more source

Adenine nucleotide translocator and ATP synthase cooperate in mediating the mitochondrial permeability transition

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Both ATP synthase and adenine nucleotide translocator (ANT) play key roles in mediating the permeability transition. The contribution of ANT becomes evident in the presence of atractylate (ATR) at pH 6.5, a condition that prevents ATP synthase channel activity. At pH 7.4, this effect is minimal, suggesting a critical role for ATP
Ludovica Tommasin   +7 more
wiley   +1 more source

Mathematical model of the zebrafish ventricular cardiomyocyte action potential and calcium transient

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend This study presents the development and validation of the first biophysically detailed computational model of the zebrafish ventricular action potential (AP). The model is based on a human cardiomyocyte framework and reparameterized using published and newly generated patch‐clamp recordings of zebrafish ionic currents.
Ludovica Cestariolo   +5 more
wiley   +1 more source

Large language models for bioinformatics

open access: yesQuantitative Biology, Volume 14, Issue 1, March 2026.
Abstract With the rapid advancements in large language model technology and the emergence of bioinformatics‐specific language models (BioLMs), there is a growing need for a comprehensive analysis of the current landscape, computational characteristics, and diverse applications.
Wei Ruan   +54 more
wiley   +1 more source

Mapping novel yellow and leaf rust loci and predicting resistance in cross derived Canadian durum wheat

open access: yesThe Plant Genome, Volume 18, Issue 4, December 2025.
Abstract Durum wheat (Triticum turgidum ssp. durum) suffers substantial yield losses from yellow rust (Puccinia striiformis) and leaf rust (Puccinia triticina). In this study, we employed genome‐wide association studies (GWAS) to identify loci associated with rust resistance and used genomic selection (GS) to evaluate the predictive accuracy of ...
Juan Menor de Gaspar   +14 more
wiley   +1 more source

Cohomotopy sets of (n−1)$(n-1)$‐connected (2n+2)$(2n+2)$‐manifolds for small n$n$

open access: yesTransactions of the London Mathematical Society, Volume 12, Issue 1, December 2025.
Abstract Let M$M$ be a closed orientable (n−1)$(n-1)$‐connected (2n+2)$(2n+2)$‐manifold, n⩾2$n\geqslant 2$. In this paper, we combine the Postnikov tower of spheres and the homotopy decomposition of the reduced suspension space ΣM$\Sigma M$ to investigate the (integral) cohomotopy sets π*(M)$\pi ^\ast (M)$ for n=2,3,4$n=2,3,4$, under the assumption ...
Pengcheng Li, Jianzhong Pan, Jie Wu
wiley   +1 more source

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