Results 31 to 40 of about 39,689 (251)
Discrete Particle Swarm Optimization for the minimum labelling Steiner tree problem [PDF]
, 2008 Particle Swarm Optimization is an evolutionary method inspired by the social behaviour of individuals inside swarms in nature. Solutions of the problem are modelled as members of the swarm which fly in the solution space.
N. Mladenović +8 more
core +1 more source
Optimal impact strategies for asteroid deflection [PDF]
, 2008 This paper presents an analysis of optimal impact strategies to deflect potentially dangerous asteroids. To compute the increase in the minimum orbit intersection distance of the asteroid due to an impact with a spacecraft, simple analytical formulas ...
Vasile, M. +3 more
core +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Multi-agent collaborative search : an agent-based memetic multi-objective optimization algorithm applied to space trajectory design [PDF]
, 2011 This article presents an algorithm for multi-objective optimization that blends together a number of heuristics. A population of agents combines heuristics that aim at exploring the search space both globally and in a neighbourhood of each agent.
Vasile, M., Zuiani, F.
core +4 more sources
Mathematical Model for Optimal Control of Soil-Transmitted Helminth Infection [PDF]
Computational and Mathematical Methods in Medicine, 2020 In this paper, we study the dynamics of soil-transmitted helminth infection. We formulate and analyse a deterministic compartmental model using nonlinear differential equations. The basic reproduction number is obtained and both disease-free and endemic equilibrium points are shown to be asymptotically stable under given threshold conditions. The model
Aristide G. Lambura +3 more
openaire +3 more sources
HIGH SPEED FUNCTIONALITY OPTIMIZATION OF FIVE-PHASE PM MACHINE USING 3RD HARMONIC CURRENT [PDF]
, 2013 This project was supported by the Laboratory of Electrical Engineering and Power Electronics (L2EP) France. It is a successive cooperation project between the control team and optimization team of the laboratory .Some surrogate-assisted optimization ...
GONG, Jinlin +4 more
core
Transverse Feedback Linearization with Partial Information for Single-Input Systems [PDF]
, 2014 “First Published in SIAM Journal on Control and Optimization in 2014, published by the Society for Industrial and Applied Mathematics (SIAM)” and the copyright notice as stated in the article itself (e.g., “Copyright © by SIAM.
Nielsen, Christopher
core +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source