Results 71 to 80 of about 52,841 (278)

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Factors Affecting Extinction After Disruption of Mating Signals. [PDF]

, 2014
The proportion of model runs that resulted in population extinction with (A) varying Disruption, (B) varying DisruptionDuration, and (C) the level of Preference at time-point A (at the paternally inherited allele immediately prior to disruption of mating
Shinichi Nakagawa (134648), Alistair McNair Senior (601955), Volker Grimm (134506)   +2 more
core   +1 more source

Pheromone gland transcriptome of the pink bollworm moth, Pectinophora gossypiella: Comparison between a laboratory and field population.

PLoS ONE, 2019
The pink bollworm, Pectinophora gossypiella, is a world-wide pest of cotton and in some parts of the cotton growing region is controlled by the mating disruption technique using synthetic sex pheromone. The sex pheromone consists of two compounds, (Z,Z)-
Xiaoyi Dou, Sijun Liu, Victoria Soroker, Ally Harari, Russell Jurenka   +4 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Mass trapping and mating disruption to control Cadra cautella (Walker) in a confectionery factory [PDF]

, 2011
A mass trapping system was established in a chocolate factory to control Cadra cautella, using plastic containers filled with water. In order to interfere with mating, a mating disruption system was applied in a confined area.
L. Suss, S. Savoldelli
core  

Mating disruption technique for the European grain moth infestations [PDF]

, 2023
Nemapogon granellus (L.) (Lepidoptera: Tineidae) is a stored-product moth, found to infest stored animal products such as meat, sausages and cheese. Damages are caused by larvae digging tunnels for feeding on cured meat and cheese.
Lupi D., Malabusini S., Guarino S., Savoldelli S., Peri S., Jucker C.   +5 more
core  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Efficacy of pheromone mating disruption for vine mealybug control [PDF]

, 2013
The vine mealybug (VMB), Planococcus ficus (Signoret), is an established vineyard pest in California along with almost all other wine grape growing regions.
Langone, David John
core   +1 more source

Is mating disruption effective in controlling the olive moth, Prays oleae? [PDF]

, 2009
Field trials were carried out from 2002 to 2004 in an olive grove near Cairo, Egypt, to evaluate the efficacy of mating disruption to control the olive moth, Prays oleae (Lepidoptera: Yponomeutidae), during the first and second generations.
Herz, Annette, Showiel, S., Hegazi, E. M., Mazomenos, B. E., Khafagi, W. E., Konstantopoulou, M. A., Agamy, E., Abdel-Rahman, S. M., Zaitun, A., Abd El-Aziz, G. M.   +9 more
core   +1 more source