Results 181 to 190 of about 13,912,764 (337)

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Cell-internal autocrine receptor inactivation supports maintenance of mating-type identity in yeast. [PDF]

Sci Adv
Anders A, Malengo G, Kley L, Sourjik V.
europepmc   +1 more source

Frequent transitions in mating-type locus chromosomal organization in Malassezia and early steps in sexual reproduction. [PDF]

Proc Natl Acad Sci U S A, 2023
Coelho MA, Ianiri G, David-Palma M, Theelen B, Goyal R, Narayanan A, Lorch JM, Sanyal K, Boekhout T, Heitman J.   +9 more
europepmc   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Establishment of a congenic strain for the oyster mushroom reveals the structure and evolution of mating-type loci. [PDF]

PLoS Genet
Lee YY, Vidal-Diez de Ulzurrun G, Tay RJ, Hsueh YP.   +3 more
europepmc   +1 more source

The Fission Yeast Mating-Type Switching Motto: "One-for-Two" and "Two-for-One". [PDF]

Microbiol Mol Biol Rev, 2023
Arcangioli B, Gangloff S.
europepmc   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Analysis of the Mating-Type Distribution and Fertility Variation in Magnaporthe oryzae Populations in China. [PDF]

J Fungi (Basel)
Yan H, Liu J, Xu H, Yang J, Dong H.
europepmc   +1 more source

Uncovering the history of recombination and population structure in western Canadian stripe rust populations through mating type alleles. [PDF]

BMC Biol, 2023
Holden S, Bakkeren G, Hubensky J, Bamrah R, Abbasi M, Qutob D, de Graaf ML, Kim SH, Kutcher HR, McCallum BD, Randhawa HS, Iqbal M, Uloth K, Burlakoti RR, Brar GS.   +14 more
europepmc   +1 more source