Results 71 to 80 of about 13,912,764 (337)

DNA polymerase α (swi7) and the flap endonuclease fen1 (rad2) act together in the s-phase alkylation damage response in S. pombe [PDF]

open access: yes, 2012
Polymerase α is an essential enzyme mainly mediating Okazaki fragment synthesis during lagging strand replication. A specific point mutation in Schizosaccharomyces pombe polymerase α named swi7-1, abolishes imprinting required for mating-type switching ...
Koulintchenko Milana   +20 more
core   +1 more source

MATING TYPES IN OXYTRICHA AND THE SIGNIFICANCE OF MATING TYPE SYSTEMS IN CILIATES

open access: yesThe Biological Bulletin, 1956
A study of Oxytricha bifaria revealed a system of nine interbreeding mating types. The mating behavior and life cycle of this organism are described. Two hypotheses which account for systems of multiple mating types in some ciliates and binary mating types in others are presented.
openaire   +3 more sources

Mating-type differentiation and mate selection in the homothallic Chlamydomonas monoica [PDF]

open access: yesCurrent Genetics, 1994
By using combinations of phenotypically-distinct--but sexually-compatible--mutant strains of C. monoica (zym-1, zym-27, and nit-2) and assaying for zygote genotypes in genetically-mixed mating populations (where gametes of the two parental homothallic strains were present at similar frequencies), we have found that matings occur preferentially between ...
van den Ende, H., VanWinkle-Swift, K.P.
openaire   +4 more sources

Contrasted patterns in mating-type chromosomes in fungi: hotspots versus coldspots of recombination

open access: yesFungal Biology Reviews, 2015
It is striking that, while central to sexual reproduction, the genomic regions determining sex or mating-types are often characterized by suppressed recombination that leads to a decrease in the efficiency of selection, shelters genetic load, and ...
A. Idnurm   +3 more
semanticscholar   +1 more source

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook   +6 more
wiley   +1 more source

Environment-induced same-sex mating in the yeast Candida albicans through the Hsf1-Hsp90 pathway.

open access: yesPLoS Biology, 2019
While sexual reproduction is pervasive in eukaryotic cells, the strategies employed by fungal species to achieve and complete sexual cycles is highly diverse and complex.
Guobo Guan   +11 more
doaj   +1 more source

Mating-type switching in S. pombe.

open access: yes, 2018
(A) The mat1 locus is expressed and confers cell type. The silent loci mat2-P and mat3-M serve as donors of genetic information to interconvert the mat1-P and mat1-M alleles.
Geneviève Thon (13482)   +4 more
core   +1 more source

The Heritability of Mating Behaviour in a Fly and Its Plasticity in Response to the Threat of Sperm Competition [PDF]

open access: yes, 2014
Phenotypic plasticity is a key mechanism by which animals can cope with rapidly changeable environments, but the evolutionary lability of such plasticity remains unclear.
Price, TA   +16 more
core   +1 more source

Increased Risk of Sarcomas in Children With Congenital Anomalies: Findings From the Genetic Overlap Between Anomalies and Cancer in Kids (GOBACK) Registry Linkage Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric sarcomas are a heterogeneous group of tumors that contribute disproportionately to cancer mortality in children. Although congenital anomalies are among the strongest known risk factors for childhood cancer, the risk of specific sarcoma subtypes among affected individuals has not yet been thoroughly evaluated. Procedure We
Russ Wolters   +17 more
wiley   +1 more source

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source

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