Results 81 to 90 of about 4,924 (174)

The Interactive Role of Climatic Transfer Distance and Overstory Retention on Douglas‐Fir Seedling Survival and Height Growth in Interior British Columbia

Global Change Biology, Volume 31, Issue 1, January 2025.
ABSTRACT The future climatic niche of interior Douglas‐fir (Pseudotsuga menziesii var. glauca [Mirb.] Franco) is expected to have little spatial overlap with its current range due to climate change. The resulting misalignment of the climatic niche and species distribution is expected to result in many forests becoming maladapted in their current ...
Thomson C. Harris, W. Jean Roach, Erin M. Miller, Suzanne W. Simard   +3 more
wiley   +1 more source

Aspect-based sentiment classification with BERT and AI feedback

Natural Language Processing Journal
Data augmentation has been widely employed in low-resource aspect-based sentiment classification (ABSC) tasks to alleviate the issue of data sparsity and enhance the performance of the model. Unlike previous data augmentation approaches that rely on back
Lingling Xu, Weiming Wang
doaj   +1 more source

Mechanistic basis for rescuing hypertrophic cardiomyopathy with myosin regulatory light chain phosphorylation

Cytoskeleton, Volume 81, Issue 12, Page 806-814, December 2024.
Abstract We investigated the impact of the phosphomimetic (Ser15 → Asp15) myosin regulatory light chain (S15D‐RLC) on the Super‐Relaxed (SRX) state of myosin using previously characterized transgenic (Tg) S15D‐D166V rescue mice, comparing them to the Hypertrophic Cardiomyopathy (HCM) Tg‐D166V model and wild‐type (WT) RLC mice. In the Tg‐D166V model, we
Jingsheng Liang, Katarzyna Kazmierczak, Melanie Veerasammy, Sunil Yadav, Lauro Takeuchi, Rosemeire Kanashiro‐Takeuchi, Danuta Szczesna‐Cordary   +6 more
wiley   +1 more source

Bacterial chromatin proteins, transcription, and DNA topology: Inseparable partners in the control of gene expression

Molecular Microbiology, Volume 122, Issue 1, Page 81-112, July 2024.
In this review article, the diverse mechanisms by which bacterial chromatin proteins influence and are influenced by transcription and DNA supercoiling are discussed. Abstract DNA in bacterial chromosomes is organized into higher‐order structures by DNA‐binding proteins called nucleoid‐associated proteins (NAPs) or bacterial chromatin proteins (BCPs ...
Christine M. Hustmyer, Robert Landick
wiley   +1 more source

Gene silencing and large-scale domain structure of the E. coli genome

, 2012
The H-NS chromosome-organizing protein in E. coli can stabilize genomic DNA loops, and form oligomeric structures connected to repression of gene expression.
Lagomarsino, Marco Cosentino, Sclavi, Bianca, Zarei, Mina   +2 more
core   +2 more sources

The metabolism of melanin synthesis—From melanocytes to melanoma

Pigment Cell &Melanoma Research, Volume 37, Issue 4, Page 438-452, July 2024.
Melanin synthesis requires coordinated metabolism across the subcellular compartments within melanocytes. In this review, the metabolism of melanin synthesis is discussed in detail with special emphasis placed on the potential intersection with melanoma tumor biology. Abstract Melanin synthesis involves the successful coordination of metabolic pathways
Marelize Snyman, Rachel Elizabeth Walsdorf, Sophia Nicole Wix, Jennifer Gibson Gill   +3 more
wiley   +1 more source

Future carbon sequestration potential in a widespread transcontinental boreal tree species: Standing genetic variation matters!

Global Change Biology, Volume 30, Issue 6, June 2024.
We explored how genetic variability of black spruce populations, shaped by their postglacial history and adaptation to local climate, affects the species' response to future climate change (CC). By analyzing tree rings and genetic data from 62 populations planted in four common gardens across Canada, we found that populations with varied postglacial ...
Etienne Robert, Patrick Lenz, Yves Bergeron, Guillaume de Lafontaine, Olivier Bouriaud, Nathalie Isabel, Martin P. Girardin   +6 more
wiley   +1 more source

Enzyme Kinetics Analysis: An online tool for analyzing enzyme initial rate data and teaching enzyme kinetics

Biochemistry and Molecular Biology Education, Volume 52, Issue 3, Page 348-358, May/June 2024.
Abstract Enzymes are nature's catalysts, mediating chemical processes in living systems. The study of enzyme function and mechanism includes defining the maximum catalytic rate and affinity for substrate/s (among other factors), referred to as enzyme kinetics.
Daniel A. Mak, Sebastian Dunn, David Coombes, Carlo R. Carere, Jane R. Allison, Volker Nock, André O. Hudson, Renwick C. J. Dobson   +7 more
wiley   +1 more source

Gene expression in Sinclair swine with malignant melanoma

Animal, 2012
Sinclair swine develop an aggressive form of melanoma, which, in many cases, spontaneously regresses after a complete metastatic phase. We used Affymetrix GeneChip® Porcine Genome Arrays consisting of 24 123 probe sets to compare gene expression in white
M. Okomo-Adhiambo, A. Rink, W.M. Rauw, L. Gomez-Raya   +3 more
doaj   +1 more source

A genome-wide association study identifies novel alleles associated with hair color and skin pigmentation.

PLoS Genetics, 2008
We conducted a multi-stage genome-wide association study of natural hair color in more than 10,000 men and women of European ancestry from the United States and Australia. An initial analysis of 528,173 single nucleotide polymorphisms (SNPs) genotyped on
Jiali Han, Peter Kraft, Hongmei Nan, Qun Guo, Constance Chen, Abrar Qureshi, Susan E Hankinson, Frank B Hu, David L Duffy, Zhen Zhen Zhao, Nicholas G Martin, Grant W Montgomery, Nicholas K Hayward, Gilles Thomas, Robert N Hoover, Stephen Chanock, David J Hunter   +16 more
doaj   +1 more source