Results 71 to 80 of about 502 (138)

Principles of bacterial genome organization, a conformational point of view

Molecular Microbiology, Volume 123, Issue 3, Page 195-205, March 2025.
Chromosome conformation capture coupled with deep sequencing (Hi‐C) has revealed the diversity of genome architectures across bacterial species, characterizing new chromosome structural layers and the activities of factors involved in their organization.
Sokrich Ponndara, Mounia Kortebi, Frédéric Boccard, Stéphanie Bury‐Moné, Virginia S. Lioy   +4 more
wiley   +1 more source

Physical models of bacterial chromosomes

Molecular Microbiology, Volume 123, Issue 2, Page 143-153, February 2025.
Connecting experimental observations to biophysical models can give rise to new insights on bacterial chromosome organization. Simple polymer models explore how physical constraints affect bacterial chromosome organization; bottom‐up mechanistic models connect these constraints to their underlying causes; and data‐driven models are inferred directly ...
Janni Harju, Chase P. Broedersz
wiley   +1 more source

Optimization of Clustering and Trajectory for Minimizing Age of Information in Unmanned Aerial Vehicle-Assisted Mobile Edge Computing Network

Sensors
With the development of the Internet of Things (IoT) technology, massive amounts of sensor data in applications such as fire monitoring need to be transmitted to edge servers for timely processing.
Huicong Shen, Die Wang, Zhen Huang, Yunjian Jia   +3 more
doaj   +1 more source

The Interactive Role of Climatic Transfer Distance and Overstory Retention on Douglas‐Fir Seedling Survival and Height Growth in Interior British Columbia

Global Change Biology, Volume 31, Issue 1, January 2025.
ABSTRACT The future climatic niche of interior Douglas‐fir (Pseudotsuga menziesii var. glauca [Mirb.] Franco) is expected to have little spatial overlap with its current range due to climate change. The resulting misalignment of the climatic niche and species distribution is expected to result in many forests becoming maladapted in their current ...
Thomson C. Harris, W. Jean Roach, Erin M. Miller, Suzanne W. Simard   +3 more
wiley   +1 more source

Gene expression in Sinclair swine with malignant melanoma

Animal, 2012
Sinclair swine develop an aggressive form of melanoma, which, in many cases, spontaneously regresses after a complete metastatic phase. We used Affymetrix GeneChip® Porcine Genome Arrays consisting of 24 123 probe sets to compare gene expression in white
M. Okomo-Adhiambo, A. Rink, W.M. Rauw, L. Gomez-Raya   +3 more
doaj   +1 more source

Mechanistic basis for rescuing hypertrophic cardiomyopathy with myosin regulatory light chain phosphorylation

Cytoskeleton, Volume 81, Issue 12, Page 806-814, December 2024.
Abstract We investigated the impact of the phosphomimetic (Ser15 → Asp15) myosin regulatory light chain (S15D‐RLC) on the Super‐Relaxed (SRX) state of myosin using previously characterized transgenic (Tg) S15D‐D166V rescue mice, comparing them to the Hypertrophic Cardiomyopathy (HCM) Tg‐D166V model and wild‐type (WT) RLC mice. In the Tg‐D166V model, we
Jingsheng Liang, Katarzyna Kazmierczak, Melanie Veerasammy, Sunil Yadav, Lauro Takeuchi, Rosemeire Kanashiro‐Takeuchi, Danuta Szczesna‐Cordary   +6 more
wiley   +1 more source

Qualidade da argumentação de estudantes da licenciatura em matemática na disciplina álgebra linear

Alexandria
Este artigo utiliza o Modelo Argumentativo Toulminiano e Perelmaniano (MATP) na disciplina de Álgebra Linear da Licenciatura em Matemática, empregando-o como orientação da estratégia de ensino e instrumento analítico. O objetivo da pesquisa é analisar a
Joilma Silva Carneiro, Elder Sales Teixeira, Andréia Maria Pereira de Oliveira   +2 more
doaj   +1 more source

A genome-wide association study identifies novel alleles associated with hair color and skin pigmentation.

PLoS Genetics, 2008
We conducted a multi-stage genome-wide association study of natural hair color in more than 10,000 men and women of European ancestry from the United States and Australia. An initial analysis of 528,173 single nucleotide polymorphisms (SNPs) genotyped on
Jiali Han, Peter Kraft, Hongmei Nan, Qun Guo, Constance Chen, Abrar Qureshi, Susan E Hankinson, Frank B Hu, David L Duffy, Zhen Zhen Zhao, Nicholas G Martin, Grant W Montgomery, Nicholas K Hayward, Gilles Thomas, Robert N Hoover, Stephen Chanock, David J Hunter   +16 more
doaj   +1 more source

Abstracts

Molecular Oncology, Volume 20, Issue S1, Page 1-692, August 2026.
Abstracts submitted to the ‘EACR 2026 Congress: Innovative Cancer Science’, from 08–11 June 2026 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source

Bacterial chromatin proteins, transcription, and DNA topology: Inseparable partners in the control of gene expression

Molecular Microbiology, Volume 122, Issue 1, Page 81-112, July 2024.
In this review article, the diverse mechanisms by which bacterial chromatin proteins influence and are influenced by transcription and DNA supercoiling are discussed. Abstract DNA in bacterial chromosomes is organized into higher‐order structures by DNA‐binding proteins called nucleoid‐associated proteins (NAPs) or bacterial chromatin proteins (BCPs ...
Christine M. Hustmyer, Robert Landick
wiley   +1 more source