Results 91 to 100 of about 9,281 (250)

Matrine combined with Osthole inhibited the PERK apoptosis of splenic lymphocytes in PCV2-infected mice model

BMC Veterinary Research, 2023
Background Porcine circovirus type 2 (PCV2) is one of the major pathogens commonly found in pigs, which causes immunosuppression and apoptosis. Vaccination and a single drug cannot totally prevent and treat PCV2 infection.
Yinlan Xu, Shuangxiu Wan, Panpan Sun, Ajab Khan, Jianhua Guo, Xiaozhong Zheng, Yaogui Sun, Kuohai Fan, Wei Yin, Hongquan Li, Na Sun   +10 more
doaj   +1 more source

Total alkaloids of Goebelia alopecuroides bge. grass obtained by microwave extraction method [PDF]

, 2017
Total composition of alkaloids obtained by microwave extraction was determined by chromatographic mass spectroscopic method. It was revealed that the major components are matrine (64.80%), sophoramin (20.71%).
Балташ, Р. М., Кокораева, А. К.   +1 more
core  

Plant-derived antivirals against hepatitis c virus infection [PDF]

, 2018
Hepatitis C virus (HCV) infection is a worldwide public health burden and it is estimated that 185 million people are or have previously been infected worldwide.
Harris, M, Jardim, ACG, Rahal, P, Shimizu, JF   +3 more
core   +1 more source

Ultrafast and Highly Efficient Laser Extraction of Matrine and Oxymatrine from Sophora flavescens for the Anticancer Activity

ACS Omega
Matrine and oxymatrine are mainly obtained from Sophora flavescens using the high-temperature and prolonged solvent extraction methods currently employed in industries.
Peishi Wu, Pingping Wang, Weiwei Cao, Ning Liu, Hang Zou, Guowei Yang   +5 more
semanticscholar   +1 more source

Ultrashort‐Pulsed Laser Diffusion Enhancement in Liquids for Cold Extraction of Coffee in an Analytically Validated Low‐Fluence Regime

Advanced Photonics Research, Volume 6, Issue 11, November 2025.
In this article, pulsed laser diffusion enhancement in liquids as an analytically validated laser extraction in liquids method of coffee suspensions in a defined low fluence window is presented. The results confirm the generation of a unique aroma profile and reduced acidity, which is neither attributed to changes in the specific surface area nor ...
Tina Friedenauer, Simela Kordhishte, Wiebke L. M. Narz, Tobias Bessel, Lucie K. Tintrop, Maryam Vosough, Amir Salemi, Cedric Thom, Sven W. Meckelmann, Maximilian Spellauge, Alexander Sommeryns, Christoph Rehbock, Torsten C. Schmidt, Oliver J. Schmitz, Heinz P. Huber, Stephan Barcikowski   +15 more
wiley   +1 more source

Antiviral Effect of Matrine against Human Enterovirus 71 [PDF]

Molecules, 2012
Human enterovirus 71, a member of the Picornaviridae family, is one of the major causative agent of hand, foot and mouth disease in children less than six years old. This illness has caused mortalities in large-scale outbreaks in the Asia-Pacific region in recent years. No vaccine or antiviral therapy is available.
Jiangning Liu, Chuan Qin, Kai Yan, Liangfeng Zhang, Xu Zhang, Jinghui Xiu, Yajun Yang   +6 more
openaire   +3 more sources

Matrine Reverses the Warburg Effect and Suppresses Colon Cancer Cell Growth via Negatively Regulating HIF-1α

Frontiers in Pharmacology, 2019
The Warburg effect is a peculiar feature of cancer’s metabolism, which is an attractive therapeutic target that could aim tumor cells while sparing normal tissue.
Xiaoting Hong, Xiaoting Hong, Linhai Zhong, Yurou Xie, Kaifeng Zheng, Jinglong Pang, Yesen Li, Yifan Yang, Xiaolin Xu, Panying Mi, Hanwei Cao, Wenqing Zhang, Tianhui Hu, Gang Song, Daxuan Wang, Yan-yan Zhan   +15 more
doaj   +1 more source

Advances in Molecularly Imprinted Polymers for Bone Biomarker Detection and Therapeutic Applications

ChemistryOpen, Volume 14, Issue 11, November 2025.
This review highlights the emerging applications of molecularly imprinted polymers (MIPs) in bone regeneration and diagnosis. MIPs facilitate osteogenic treatments by guiding stem cell differentiation and delivering bioactive molecules and enable precise detection of bone turnover biomarkers via MIP‐based sensors, offering promising strategies for next‐
Ren Yang, Xiaohan Ma, Mingcheng Xuan, Yingqi Ma, Jiexian Ding, David Y. S. Chau, Jonathan C. Knowles, Feng Peng, Alessandro Poma   +8 more
wiley   +1 more source

Matrine Attenuates COX-2 and ICAM-1 Expressions in Human Lung Epithelial Cells and Prevents Acute Lung Injury in LPS-Induced Mice

Mediators of Inflammation, 2016
Matrine is isolated from Sophora flavescens and shows anti-inflammatory effects in macrophages. Here we evaluated matrine’s suppressive effects on cyclooxygenase 2 (COX-2) and intercellular adhesion molecule-1 (ICAM-1) expressions in lipopolysaccharide- (
Chian-Jiun Liou, You-Rong Lai, Ya-Ling Chen, Yi-Hsien Chang, Zih-Ying Li, Wen-Chung Huang   +5 more
doaj   +1 more source

Vascularized Tumor‐on‐a‐Chip Model as a Platform for Studying Tumor‐Microenvironment‐Drug Interaction

Macromolecular Bioscience, Volume 25, Issue 10, October 2025.
Vascularized tumor‐on‐a‐chip platforms replicate human tumor microenvironments by integrating perfusable vessels and stromal elements in microfluidic systems. These models enable dynamic assessment of drug delivery and therapeutic response under physiologically relevant flow, offering enhanced predictive value for cancer treatment.
Hyelim Kim, Seung‐Woo Cho, Hong Nam Kim   +2 more
wiley   +1 more source