Results 71 to 80 of about 1,668,606 (328)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Characterization of Chemically Treated Limonia Acidissima (Wood Apple) Shell Powder: Physicochemical, Thermal, and Morphological Properties

Journal of Natural Fibers, 2022
The latest environmental legislations imposed by various governments across the globe have made exceptional utilization of biodegradable (green) materials in composite structures.
Vasantha Kumar Shravanabelagola Nagaraja Setty, Govardhan Goud, Sharath Peramanahalli Chikkegowda, Sanjay Mavinkere Rangappa, Suchart Siengchin   +4 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Extraction and Characterization of Sponge Gourd Outer Skin Fiber

Journal of Natural Fibers, 2023
Plant-derived natural fibers have recently been used as a promising reinforcement in polymer matrix composites. Fibers from the inner sponge of the luffa cylindrica fruit have been the subject of several studies as reinforcement in various polymer resins.
Felix Sahayaraj A, Muthukrishnan M, Jenish I   +2 more
doaj   +1 more source

Reentrant topological transitions in a quantum wire/superconductor system with quasiperiodic lattice modulation [PDF]

, 2012
We study the condition for a topological superconductor (TS) phase with end Majorana fermions to appear when a quasiperiodic lattice modulation is applied to a one-dimensional quantum wire with strong spin-orbit interaction situated under a magnetic ...
Kawakami, Norio, Tezuka, Masaki
core   +2 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

A Distinguishable Role of eDNA in the Viscoelastic Relaxation of Biofilms

mBio, 2013
Bacteria in the biofilm mode of growth are protected against chemical and mechanical stresses. Biofilms are composed, for the most part, of extracellular polymeric substances (EPSs). The extracellular matrix is composed of different chemical constituents,
Brandon W. Peterson, Henny C. van der Mei, Jelmer Sjollema, Henk J. Busscher, Prashant K. Sharma   +4 more
doaj   +1 more source

Monitoring and simulations of hydrolysis in epoxy matrix composites during hygrothermal aging [PDF]

, 2014
In this paper, we studied the water transport in thermoset matrices. We used Fourier Transform Infrared analysis (FTIR) during sorption/desorption experiments to investigate the interaction between sorbed water and the epoxy network.
EL YAGOUBI, Jalal, LUBINEAU, Gilles, TRAIDIA, Abderrazak, VERDU, Jacques   +3 more
core   +4 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source