Results 81 to 90 of about 164,304 (297)

Poisson Matrix Recovery and Completion [PDF]

open access: yesIEEE Transactions on Signal Processing, 2016
Submitted to IEEE Journal. Parts of the paper have appeared in GlobalSIP 2013, GlobalSIP 2014, and ISIT 2015.
Yang Cao 0013, Yao Xie 0002
openaire   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Toeplitz matrix completion via a low-rank approximation algorithm

open access: yesJournal of Inequalities and Applications, 2020
In this paper, we propose a low-rank matrix approximation algorithm for solving the Toeplitz matrix completion (TMC) problem. The approximation matrix was obtained by the mean projection operator on the set of feasible Toeplitz matrices for every ...
Ruiping Wen, Yaru Fu
doaj   +1 more source

On traffic matrix completion in the internet [PDF]

open access: yesProceedings of the 2012 Internet Measurement Conference, 2012
The ability of an ISP to infer traffic volumes that are not directly measurable can be useful for research, engineering, and business intelligence. Previous work has shown that traffic matrix completion is possible, but there is as yet no clear understanding of which ASes are likely to be able to perform TM completion, and which traffic flows can be ...
Gursun, Gonca, Crovella, Mark
openaire   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Adaptive Noisy Matrix Completion

open access: yesCoRR, 2022
Low-rank matrix completion has been studied extensively under various type of categories. The problem could be categorized as noisy completion or exact completion, also active or passive completion algorithms. In this paper we focus on adaptive matrix completion with bounded type of noise.
openaire   +2 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Matrix completion with structure [PDF]

open access: yes, 2016
Often, data organized in matrix form contains missing entries. Further, such data has been observed to exhibit effective low-rank, and has led to interest in the particular problem of low-rank matrix-completion: Given a partially-observed matrix ...
Ruchansky, Natali
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

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