Results 61 to 70 of about 7,271,767 (336)

Partial Realization Theory and System Identification Redux

, 2017
Some twenty years ago we introduced a nonstandard matrix Riccati equation to solve the partial stochastic realization problem. In this paper we provide a new derivation of this equation in the context of system identification. This allows us to show that
Lindquist, Anders
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Kronecker product of matrices and solutions of Sylvestertype matrix polynomial equations

Математичні Студії
We investigate the solutions of the Sylvester-type matrix polynomial equation $$A(\lambda)X(\lambda)+Y(\lambda)B(\lambda)=C(\lambda),$$ where\ $A(\lambda),$ \ $ B(\lambda),$\ and \ $C(\lambda)$ are the polynomial matrices with elements in a ring of ...
N. S. Dzhaliuk, V. M. Petrychkovych
doaj   +1 more source

Spectral analysis of variable-order multi-terms fractional differential equations

Open Physics, 2023
In this work, a numerical scheme based on shifted Jacobi polynomials (SJPs) is deduced for variable-order fractional differential equations (FDEs). We find numerical solution of consider problem of fractional order. The proposed numerical scheme is based
Shah Kamal, Abdeljawad Thabet, Jeelani Mdi Begum, Alqudah Manar A.   +3 more
doaj   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

H-representation method for solving reduced biquaternion matrix equation

Mathematical Modelling and Control, 2022
In this paper, we study the Hankel and Toeplitz solutions of reduced biquaternion matrix equation (1.1). Using semi-tensor product of matrices, the reduced biquaternion matrix equation (1.1) can be transformed into a general matrix equation of the form ...
Xueling Fan, Ying Li, Wenxv Ding, Jianli Zhao   +3 more
doaj   +1 more source

Nonlinear dynamics of open quantum systems

, 2017
The evolution of a composite closed system using the integral wave equation with the kernel in the form of path integral is considered. It is supposed that a quantum particle is a subsystem of this system.
Samarin, A. Yu.
core   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Matrix equation representation of the convolution equation and its unique solvability

Special Matrices
We consider the convolution equation F*X=BF* X=B, where F∈R3×3F\in {{\mathbb{R}}}^{3\times 3} and B∈Rm×nB\in {{\mathbb{R}}}^{m\times n} are given and X∈Rm×nX\in {{\mathbb{R}}}^{m\times n} is to be determined. The convolution equation can be regarded as a
Satake Yuki, Sogabe Tomohiro, Kemmochi Tomoya, Zhang Shao-Liang   +3 more
doaj   +1 more source