Results 51 to 60 of about 127,181 (241)
Integrable Structure of the Dirichlet Boundary Problem in Multiply-Connected Domains
We study the integrable structure of the Dirichlet boundary problem in two dimensions and extend the approach to the case of planar multiply-connected domains.
A Zabrodin +12 more
core +1 more source
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
On generalized Melvin solutions for Lie algebras of rank 3
Generalized Melvin solutions for rank-$3$ Lie algebras $A_3$, $B_3$ and $C_3$ are considered. Any solution contains metric, three Abelian 2-forms and three scalar fields. It is governed by three moduli functions $H_1(z),H_2(z),H_3(z)$ ($z = \rho^2$ and $\
Bolokhov, S. V., Ivashchuk, V. D.
core +1 more source
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Matrix Capelli identities related to reflection equation algebra [PDF]
Dimitri Gurevich +2 more
openalex +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Renormalization of the Sigma-Omega model within the framework of U(1) gauge symmetry
It is shown that the Sigma-Omega model which is widely used in the study of nuclear relativistic many-body problem can exactly be treated as an Abelian massive gauge field theory. The quantization of this theory can perfectly be performed by means of the
A. A. Slavnov +24 more
core +3 more sources
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source

