Results 61 to 70 of about 5,169 (253)

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Highly Accurate Galerkin Approach for Modified Anomalous Time-Fractional Sub-Diffusion Equations Based on Fibonacci Coefficient Polynomials

Fractal and Fractional
A spectral Galerkin algorithm is developed for the numerical treatment of modified anomalous time-fractional sub-diffusion equations (MATFSDEs). The algorithm is constructed using Fibonacci coefficient polynomials, from which two space–time trial ...
Mohamed Adel, Waleed Mohamed Abd-Elhameed, Naher Mohammed A. Alsafri, Mohamed Abbas El-Naggar, Ahmed Gamal Atta   +4 more
doaj   +1 more source

Anti-commuting Solutions of the Yang-Baxter-like Matrix Equation for Identity Matrix Minus Special Rank-three Matrices

Suppose \( A=I-PQ^T, \) where both \( P \)and \( Q \) are \( n\times 3 \) complex matrices and det\( (Q^T P)\neq 0 \). By analyzing the Jordan canonical form of the coefficient matrix \( A, \) we find all the anti-commuting solutions \( X, \) which satisfy \( AX=-XA, \) of the Yang-Baxter-like matrix equation(YBME) \( AXA=XAX \).
Xianghui Wen, Di Zhao, Hongyi Li
openaire   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Lagrangian structures and multidimensional consistency [PDF]

, 2010
The conventional point of view is that the Lagrangian is a scalar object (or equivalently a volume form), which through the Euler-Lagrange equations provides us with one single equation (i.e., one per component of the dependent variable ...
Lobb, Sarah Beverley
core   +3 more sources

Obtaining Some Identities With thenthPower of a Matrix Under the LorentzianProduct

, 2020
The Fibonacci number sequence and related calculations come up in scientific facts in many events that we encounterin daily life. This special number sequence is processed in the occurrence of many events such as calculating the diameter ofthe equatorial
Gökcan, İbrahim, Değer, Ali Hikmet
core  

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

On the Solutions of the Matrix Equation f(X,X^*)=g(X,X^*)

, 1972
It is well known that the matrix identities XX*=I, X=X* and XX* = X*X, where X is a square matrix with complex elements, X* is the conjugate transpose of X and I is the identity matrix, characterize unitary, hermitian and normal matrices respectively ...
P. Basavappa
core   +1 more source