Results 81 to 90 of about 4,984 (251)

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

New Identities and Equation Solutions Involving k-Oresme and k-Oresme–Lucas Sequences

Mathematics
Number sequences are among the research areas of interest in both number theory and linear algebra. In particular, the study of matrix representations of recursive sequences is important in revealing the structural properties of these sequences.
Bahar Demirtürk
doaj   +1 more source

Obtaining Some Identities With thenthPower of a Matrix Under the LorentzianProduct

, 2020
The Fibonacci number sequence and related calculations come up in scientific facts in many events that we encounterin daily life. This special number sequence is processed in the occurrence of many events such as calculating the diameter ofthe equatorial
Gökcan, İbrahim, Değer, Ali Hikmet
core  

Z(_N)-symmetric field theories and the thermodynamic Bethe ansatz [PDF]

, 1996
This thesis is concerned with perturbed conformal field theory, the thermodynamic Bethe ansatz technique and applications to statistical mechanics. In particular, the phase space of two dimensional Z(_N)-symmetric statistical models is examined using ...
Thompson, K.E., Thompson, Kevin Edward
core  

An algebraic approach to the scattering equations [PDF]

, 2015
We employ the so-called companion matrix method from computational algebraic geometry, tailored for zero-dimensional ideals, to study the scattering equations.
Junjie Rao, Yang-Hui He, Bo Feng, Feng, B., He, Y., Huang, R., Rijun Huang, Rao, J.   +7 more
core   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

3-Parameter Generalized Quaternions and Dual Quaternions with Repunit Number Components

Analele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica
In this paper, our first aim is to combine the 3-parameter generalized quaternions, which are a general form of the quaternion algebra according to 3-parameters, and repunit numbers, which are created by integer numbers that are expressed in the decimal ...
Kösal Işıl Arda, Tosun Murat
doaj   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi, Katharine Lee, Kerry C. Nix, Miguel Menchaca, Xiwei Shé, Lorelei Santa Maria, Wei Wu, Zihuai He, Fiona M. Baumer   +8 more
wiley   +1 more source

GAD65 Antibody ELISA With Extended Reportable Range: Validation and Guidance for Neurological Practice

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To (1) validate GAD65‐ELISA detection and quantification for type 1 diabetes mellitus and autoimmune neurological diagnoses, (2) correlate ELISA results (reference range < 5 IU/mL) with established radioimmunoprecipitation assay (RIA; ≤ 0.02 nmol/L), and (3) define ELISA clinical utility and pitfalls.
Andrew McKeon, Dana Olofson, Diana Anissian, Divyanshu Dubey, Eoin P. Flanagan, Max C. Herman, Sarosh R. Irani, Daniel H. Lachance, Maria A. Willrich, Sean Pittock, John R. Mills, Anastasia Zekeridou   +11 more
wiley   +1 more source