Results 81 to 90 of about 1,630,238 (295)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
A nonsymmetrical matrix and its factorizations
Mathematica Slovaca, 2019 Abstract We introduce a nonsymmetric matrix defined by q-integers. Explicit formulæ are derived for its LU-decomposition, the inverse matrices L −1 and U −1 and its inverse. Nonsymmetric variants of the Filbert and Lilbert matrices come out as consequences of our results for special choices of q and ...
Arikan, Talha +2 more
openaire +4 more sources
Evolving Matrix-Factorization-Based Collaborative Filtering Using Genetic Programming
Applied Sciences, 2020 Recommender systems aim to estimate the judgment or opinion that a user might offer to an item. Matrix-factorization-based collaborative filtering typifies both users and items as vectors of factors inferred from item rating patterns.
Raúl Lara-Cabrera +3 more
doaj +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Discrete matrix factorization cross-modal hashing with multi-similarity consistency
Complex & Intelligent Systems, 2022 Recently, matrix factorization-based hashing has gained wide attention because of its strong subspace learning ability and high search efficiency. However, some problems need to be further addressed.
Yiru Li +6 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Empirical Bayes Matrix Factorization
Journal of machine learning research : JMLR, 2018 Matrix factorization methods - including Factor analysis (FA), and Principal Components Analysis (PCA) - are widely used for inferring and summarizing structure in multivariate data. Many matrix factorization methods exist, corresponding to different assumptions on the elements of the underlying matrix factors.
Wei Wang, Matthew Stephens
openaire +5 more sources
Solution to the General Inner-Outer and Spectral Factorization Problems [PDF]
, 1998 In this paper we solve two open problems in linear system theory: the computation of the spectral and inner-outer factorizations of a rational matrix G in the most general setting.
Varga, A., Oara, C.
core
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source