Results 91 to 100 of about 13,801,421 (357)

Integrative systems‐level analysis reveals a contextual crosstalk between hypoxia and global metabolism in human breast tumors

Molecular Oncology, EarlyView.
Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam, Salem Chouaib, Mohammad Askandar Iqbal   +2 more
wiley   +1 more source

Exact Expressions for Kullback–Leibler Divergence for Multivariate and Matrix-Variate Distributions

Entropy
The Kullback–Leibler divergence is a measure of the divergence between two probability distributions, often used in statistics and information theory. However, exact expressions for it are not known for multivariate or matrix-variate distributions apart ...
Victor Nawa, Saralees Nadarajah
doaj   +1 more source

Formalization of Function Matrix Theory in HOL

Journal of Applied Mathematics, 2014
Function matrices, in which elements are functions rather than numbers, are widely used in model analysis of dynamic systems such as control systems and robotics.
Zhiping Shi, Zhenke Liu, Yong Guan, Shiwei Ye, Jie Zhang, Hongxing Wei   +5 more
doaj   +1 more source

$\mathrm{BC}_{2}$-Type Multivariable Matrix Functions and Matrix Spherical Functions [PDF]

Publications of the Research Institute for Mathematical Sciences
Matrix spherical functions associated to the compact symmetric pair (\mathrm{SU}(m+2), \mathrm{S}(\mathrm{U}(2)\times \mathrm{U}(m))) , m\geq 2 , having a reduced root system of type \mathrm{BC}_{2}
Koelink, H.T., Koelink, H.T., Liu, J.
openaire   +2 more sources

Obesity alters the fitness of peritumoral adipose tissue, exacerbating tumor invasiveness in renal cancer through the induction of ADAM12 and CYP1B1

Molecular Oncology, EarlyView.
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad, Caterina Miro, Annarita Nappi, Francesco Del Giudice, Annunziata Gaetana Cicatiello, Serena Sagliocchi, Lucia Acampora, Federica Restolfer, Melania Murolo, Emery Di Cicco, Federico Capone, Ciro Imbimbo, Monica Dentice, Felice Crocetto   +13 more
wiley   +1 more source

Addressing persistent challenges in digital image analysis of cancer tissue: resources developed from a hackathon

Molecular Oncology, EarlyView.
Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran, Clarence Yapp, Gregory J. Baker, Johanna Beyer, Young Hwan Chang, Allison L. Creason, Robert Krueger, Jeremy Muhlich, Nathan Heath Patterson, Kevin Sidak, Damir Sudar, Adam J. Taylor, Luke Ternes, Jakob Troidl, Xie Yubin, Artem Sokolov, Darren R. Tyson   +16 more
wiley   +1 more source

Development and Characterisation of an in vitro Model of Wallerian Degeneration

Frontiers in Bioengineering and Biotechnology, 2020
Following peripheral nerve injury, a sequence of events termed Wallerian degeneration (WD) takes place at the distal stump in order to allow the regenerating axons to grow back toward the target organs.
Heba Elsayed, Heba Elsayed, Alessandro Faroni, Mohammad R. Ashraf, Judith Osuji, Lydia Wunderley, Ling Zhang, Hesham Elsobky, Mohamed Mansour, Ashraf S. Zidan, Ashraf S. Zidan, Adam J. Reid, Adam J. Reid   +12 more
doaj   +1 more source

RETRACTED: On Humbert matrix functions

Journal of the Egyptian Mathematical Society, 2012
This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy).This article has been retracted at the request of the Editor-in-Chief.The authors have plagiarized part of a paper that had already appeared in Afrika Mathematika, 2012, 1–9.
M. Abul-Dahab, Ayman Shehata
openaire   +3 more sources

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

Molecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy, Heather Fairfield, Victoria E. DeMambro, Samaa Fadel, Carlos A. Gartner, Michelle Karam, Christian Potts, Princess Rodriguez, Ya‐Wei Qiang, Habib Hamidi, Xiangnan Guan, Calvin P. H. Vary, Michaela R. Reagan   +12 more
wiley   +1 more source

Vector-Valued Polynomials and a Matrix Weight Function with B2-Action. II

Symmetry, Integrability and Geometry: Methods and Applications, 2013
This is a sequel to [SIGMA 9 (2013), 007, 23 pages], in which there is a construction of a 2×2 positive-definite matrix function K(x) on R^2. The entries of K(x) are expressed in terms of hypergeometric functions. This matrix is used in the formula for a
Charles F. Dunkl
doaj   +1 more source