Results 81 to 90 of about 1,484,501 (262)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

A matrix inequality for matrix monotone functions

open access: yesInternational Journal of Algebra, 2014
In this note, we obtain a matrix inequality for matrix monotone functions, which is a generalization of an inequality due to Audenaert [Linear Algebra Appl. 422(2007)279-283].
Jiewu Huang, Limin Zou
openaire   +1 more source

L’Hospital rule for matrix functions

open access: yesJournal of the Egyptian Mathematical Society, 2013
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Kishka, Z.M.   +3 more
openaire   +2 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

The sharp square function estimate with matrix weight

open access: yesDiscrete Analysis, 2019
The sharp square function estimate with matrix weight, Discrete Analysis 2019:2, 8 pp. A central theme in harmonic analysis is to determine whether naturally occurring operators are bounded with respect to naturally occurring norms.
Tuomas Hytönen   +2 more
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Generalized Extended Matrix Variate Beta and Gamma Functions and Their Applications

open access: yesIngeniería y Ciencia, 2016
In this article, we define and study generalized forms of extended matrix variate gamma and beta functions. By using a number of results from matrix algebra, special functions of matrix arguments and zonal polynomials we derive a number of properties of ...
Daya K. Nagar   +2 more
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

A New Method of Creating Technology/Function Matrix for Systematic Innovation without Expert

open access: yesJournal of Technology Management & Innovation, 2012
The technology/function matrix is comprised by specific technologies and functions, and through the technology/function matrix we can known what the technologies with functions have opportunities for innovation of product or technology.
Tien-Yuan Cheng
doaj   +1 more source

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