Results 71 to 80 of about 4,454,720 (286)

On the Anti-Wishart distribution

, 2001
We provide the probability distribution function of matrix elements each of which is the inner product of two vectors. The vectors we are considering here are independently distributed but not necessarily Gaussian variables.
Brody, Fyodorov, Maslov, Verbaarschot, Wishart, Yi-Cheng Zhang, Yi-Kuo Yu, Yu   +7 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

An Efficient Algorithm for Basic Elementary Matrix Functions with Specified Accuracy and Application

AppliedMath
If the matrix function f(At) posses the properties of f(At)=gf(tkA, then the recurrence formula fi−1=gfi,i=N,N−1,⋯,1,f(tA)=f0, can be established. Here, fN=f(AN)=∑j=0majANj,AN=tkNA. This provides an algorithm for computing the matrix function f(At).
Huizeng Qin, Youmin Lu
doaj   +1 more source

Generalized matrix functions, determinant and permanent

پژوهش‌های ریاضی, 2022
Introduction Since linear and multilinear algebra has many applications in different branches of sciences, the attention of many mathematicians has been attracted to it in recent decades. The determinant and the permanent are the most important functions
Mohammad Hossein Jafari, Ali Reza Madadi
doaj  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

The enamel organic matrix: structure and function

Brazilian Journal of Oral Sciences, 2015
Dental enamel is the most mineralized tissue in the vertebrate body and contains the largest known biologically formed hydroxyapatite crystals. Its formation occurs extracellularly through the collaboration of a proteic transient framework (the enamel ...
Alexandre Ribeiro Espírito Santo, Sérgio Roberto Peres Line   +1 more
doaj   +1 more source

A remark on zeta functions of finite graphs via quantum walks

, 2014
From the viewpoint of quantum walks, the Ihara zeta function of a finite graph can be said to be closely related to its evolution matrix. In this note we introduce another kind of zeta function of a graph, which is closely related to, as to say, the ...
Higuchi, Yu., Konno, N., Sato, I., Segawa, E.   +3 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Self-dual noncommutative \phi^4-theory in four dimensions is a non-perturbatively solvable and non-trivial quantum field theory

, 2013
We study quartic matrix models with partition function Z[E,J]=\int dM \exp(trace(JM-EM^2-(\lambda/4)M^4)). The integral is over the space of Hermitean NxN-matrices, the external matrix E encodes the dynamics, \lambda>0 is a scalar coupling constant and ...
A. Connes, A.A. Belavin, A.S. Wightman, A.S. Wightman, C. Avramescu, C.R. Hagen, D. Friedan, D.C. Brydges, D.J. Gross, D.J. Gross, D.J. Gross, E. Brezin, E. Ising, E. Witten, E. Witten, E.H. Lieb, F.G. Tricomi, G.’t. Hooft, G.’t. Hooft, H. Bethe, Harald Grosse, I.S. Gradshteyn, J. Feldman, J. Fröhlich, J. Ginibre, J. Glimm, J. Glimm, J. Glimm, J. Schwinger, J. Wess, J.S. Feldman, J.S. Schwinger, K. Gawedzki, K. Johnson, K. Osterwalder, K. Osterwalder, K.G. Wilson, L. Onsager, L.D. Faddeev, M. Aizenman, M. Kac, M. Kontsevich, M.R. Douglas, N.I. Muskhelishvili, R. Haag, R. Haag, R.F. Streater, R.J. Baxter, R.J. Baxter, Raimar Wulkenhaar, T. Carleman, T. Filk, V. Rivasseau, V. Rivasseau, W.E. Thirring   +54 more
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source