Results 101 to 110 of about 4,444,439 (338)

A Non-monotone Alternating Updating Method for A Class of Matrix Factorization Problems

, 2018
In this paper we consider a general matrix factorization model which covers a large class of existing models with many applications in areas such as machine learning and imaging sciences.
Chen, Xiaojun, Pong, Ting Kei, Yang, Lei
core   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Development and Characterisation of an in vitro Model of Wallerian Degeneration

Frontiers in Bioengineering and Biotechnology, 2020
Following peripheral nerve injury, a sequence of events termed Wallerian degeneration (WD) takes place at the distal stump in order to allow the regenerating axons to grow back toward the target organs.
Heba Elsayed, Heba Elsayed, Alessandro Faroni, Mohammad R. Ashraf, Judith Osuji, Lydia Wunderley, Ling Zhang, Hesham Elsobky, Mohamed Mansour, Ashraf S. Zidan, Ashraf S. Zidan, Adam J. Reid, Adam J. Reid   +12 more
doaj   +1 more source

Bivariate matrix functions [PDF]

Operators and Matrices, 2014
A definition of bivariate matrix functions is introduced and some theoretical as well as algorithmic aspects are analyzed. It is shown that our framework naturally extends the usual notion of (univariate) matrix functions and allows to unify existing results on linear matrix equations and derivatives of matrix functions.
openaire   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Vector-Valued Polynomials and a Matrix Weight Function with B2-Action. II

Symmetry, Integrability and Geometry: Methods and Applications, 2013
This is a sequel to [SIGMA 9 (2013), 007, 23 pages], in which there is a construction of a 2×2 positive-definite matrix function K(x) on R^2. The entries of K(x) are expressed in terms of hypergeometric functions. This matrix is used in the formula for a
Charles F. Dunkl
doaj   +1 more source

Jost asymptotics for matrix orthogonal polynomials on the real line

, 2011
We obtain matrix-valued Jost asymptotics for block Jacobi matrices under an L1-type condition on Jacobi parameters, and give a necessary and sufficient condition for an analytic matrix-valued function to be the Jost function of a block Jacobi matrix with
Kozhan, Rostyslav
core  

Spectral analysis of gluonic pole matrix elements for fragmentation

, 2008
The non-vanishing of gluonic pole matrix elements can explain the appearance of single spin asymmetries in high-energy scattering processes. We use a spectator framework approach to investigate the spectral properties of quark-quark-gluon correlators and
A. Mukherjee, A. V. Efremov, L. P. Gamberg, P. J. Mulders   +3 more
core   +2 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Exploring the Extended Beta-Logarithmic Function: Matrix Arguments and Properties

Mathematics
The beta-logarithmic function substantially generalizes the standard beta function, which is widely recognized for its significance in many applications.
Mohammed Z. Alqarni
doaj   +1 more source