Results 81 to 90 of about 4,444,439 (338)

The enamel organic matrix: structure and function

open access: yesBrazilian Journal of Oral Sciences, 2015
Dental enamel is the most mineralized tissue in the vertebrate body and contains the largest known biologically formed hydroxyapatite crystals. Its formation occurs extracellularly through the collaboration of a proteic transient framework (the enamel ...
Alexandre Ribeiro Espírito Santo   +1 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

A Perspective Approach for Characterization of Lieb Concavity Theorem

open access: yesDemonstratio Mathematica, 2016
Lieb’s extension theorem holds for generalized p + q ∈ [0; 1] and Ando convexity theorem holds for q - r > 1. In this paper, we give a complete characterization for concavity or convexity of Lieb well known theorem in the case where p + q ≥ 1 or p+q ≤ 0.
Nikoufar Ismail
doaj   +1 more source

THE GENERALIZED Q-BESSEL MATRIX FUNCTION OF TWO VARIABLES

open access: yesمجلّة جامعة عدن للعلوم الأساسيّة والتّطبيقيّة, 2020
The Bessel function is probably the best known special function, within pure and applied mathematics. In this paper, we introduce the generalized q-analogue Bessel matrix function of two variables.
Fadhl S. N. Alsarahi
doaj   +1 more source

On Matrix-Valued Herglotz Functions [PDF]

open access: yesMathematische Nachrichten, 2000
We provide a comprehensive analysis of matrix-valued Herglotz functions and illustrate their applications in the spectral theory of self-adjoint Hamiltonian systems including matrix-valued Schr dinger and Dirac-type operators. Special emphasis is devoted to appropriate matrix-valued extensions of the well-known Aronszajn-Donoghue theory concerning ...
Gesztesy, Fritz, Tsekanovskii, Eduard
openaire   +3 more sources

On the Role of Density Matrices in Bohmian Mechanics

open access: yes, 2003
It is well known that density matrices can be used in quantum mechanics to represent the information available to an observer about either a system with a random wave function (``statistical mixture'') or a system that is entangled with another system (``
D. Dürr   +11 more
core   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

open access: yesFEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom   +3 more
wiley   +1 more source

Generally Covariant Actions for Multiple D-branes

open access: yes, 2004
We develop a formalism that allows us to write actions for multiple D-branes with manifest general covariance. While the matrix coordinates of the D-branes have a complicated transformation law under coordinate transformations, we find that these may be ...
A. Connes   +21 more
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

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