Results 21 to 30 of about 97,127 (208)
On the structure of semigroups on $L_p$ with a bounded $H{^\infty}$-calculus
, 2014 We show that a bounded analytic semigroup on an $L_p$-space has a bounded $H^{\infty}(\Sigma_{\varphi})$-calculus for some $\varphi < \frac{\pi}{2}$ if and only if the semigroup can be obtained, after restricting to invariant subspaces, factorizing ...
Fackler, Stephan
core +1 more source
Functional calculus for generators of symmetric contraction semigroups [PDF]
, 2014 We prove that every generator of a symmetric contraction semigroup on a $\sigma$-finite measure space admits, for ...
Carbonaro, Andrea, Dragičević, Oliver
core +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Some Results of R-Matrix Functions and Their Fractional Calculus
Fractal and FractionalIn this study, we explore various fractional integral properties of R-matrix functions using the Hilfer fractional derivative operator within the framework of fractional calculus.
Mohra Zayed, Ahmed Bakhet
doaj +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Cauchy integrals for the p-Laplace equation in planar Lipschitz domains
, 2014 We construct solutions to p-Laplace type equations in unbounded Lipschitz domains in the plane with prescribed boundary data in appropriate fractional Sobolev spaces.
Nyström, Kaj, Rosén, Andreas
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source