Results 41 to 50 of about 97,127 (208)
Spontaneous quantization of the Yang–Mills gradient flow
Nuclear Physics BWe formulate a nonsingular loop–space calculus for the Yang–Mills (YM) gradient flow directly in terms of Wilson loop functionals, rather than the underlying gauge fields.
Alexander Migdal
doaj +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Finite group gauge theory on graphs and gravity-like modes
Nuclear Physics BWe study gauge theory with finite group G on a graph X using noncommutative differential geometry and Hopf algebra methods with G-valued holonomies replaced by gauge fields valued in a ‘finite group Lie algebra’ subset of the group algebra CG ...
Shahn Majid, Francisco Simão
doaj +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Multidual Complex Numbers and the Hyperholomorphicity of Multidual Complex-Valued Functions
AxiomsWe develop a rigorous algebraic–analytic framework for multidual complex numbers DCn within the setting of Clifford analysis and establish a comprehensive theory of hyperholomorphic multidual complex-valued functions.
Ji Eun Kim
doaj +1 more source
Some Considerations on Discrete Quantum Gravity
, 2012 Recent results in Local Regge Calculus are confronted with Spin Foam Formalism. Introducing Barrett-Crane Quantization in Local Regge Calculus makes it possible to associate a unique Spin $j_{h}$ with an hinge $h$, fulfilling one of the requirements of ...
Gionti, Gabriele, J, S.
core +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Quantum gauge theories on noncommutative 3-d space
, 2014 We consider a class of gauge invariant models on the noncommutative space $\mathbb{R}^3_\lambda$, a deformation of $\mathbb{R}^3$. Focusing on massless models with no linear $A_i$ dependence, we obtain noncommutative gauge models for which the ...
Géré, Antoine +2 more
core +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Error structures and parameter estimation [PDF]
, 2006 This article proposes a link between statistics and the theory of Dirichlet forms used to compute errors. The error calculus based on Dirichlet forms is an extension of classical Gauss' approach to error propagation.
Bouleau, Nicolas, Chorro, Christophe
core +3 more sources