Results 61 to 70 of about 1,744,463 (240)
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
The Application Domain of Infinite Matrices with Algorithms
Universal Journal of Mathematics and Applications, 2018 The purpose of this paper is twofold. First, we define the new spaces and investigate some topological and structural properties. Also, we compute dual spaces of new spaces which are help us in the characterization of matrix mappings.
Murat Kirişçi
doaj +1 more source
Related Suzuki-type fixed point theorems in ordered metric space
Fixed Point Theory and Applications, 2020 In this paper, we use Suzuki-type contraction to prove three fixed point theorems for generalized contractions in an ordered space equipped with two metrics; we obtain some generalizations of the Kannan fixed point theorem.
Outass Rida +2 more
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FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
Comparing the paths of Hedgehog release in artificial and natural settings
FEBS Letters, EarlyView.Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley +1 more source
The Abel-type transformations into ℓ
International Journal of Mathematics and Mathematical Sciences, 1999 Let t be a sequence in (0,1) that converges to 1, and define the Abel-type matrix Aα,t by ank=(k+α k)tnk+1(1−tn)α+1 for α>−1. The matrix Aα,t determines a sequence-to-sequence variant of the Abel-type power series method of summability introduced by ...
Mulatu Lemma
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The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
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Some Tauberian theorems for Euler and Borel summability
International Journal of Mathematics and Mathematical Sciences, 1980 The well-known summability methods of Euler and Borel are studied as mappings from ℓ1 into ℓ1. In this ℓ−ℓ setting, the following Tauberian results are proved: if x is a sequence that is mapped into ℓ1 by the Euler-Knopp method Er with r>0 (or the Borel ...
J. A. Fridy, K. L. Roberts
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source