Results 61 to 70 of about 1,579,901 (232)
p63 transcriptionally regulates the expression of matrix metallopeptidase 13
Oncotarget, 2014 p63 is a transcriptional factor belonging to p53 family of genes. Beside the role in cancer, partially shared with p53 and the other member p73, p63 also plays exclusive roles in development and homeostasis of ectodermal/epidermal-related organs. Here we show that p63 transcriptionally controls the expression of the matrix metallopeptidase 13 (MMP13 ...
CELARDO, MARIA TERESA +4 more
openaire +5 more sources
Advanced Healthcare Materials, EarlyView.We developed a patient‐derived, functional microfluidic model of the diffuse midline glioma (DMG) blood–brain–tumor barrier (BBTB) comprised of endothelial cells, astrocytes, pericytes, and tumor cells. The system forms perfusable microvasculature, reveals the BBTB retains vascular integrity, identifies DMG‐specific transcriptomic changes distinct from
Kimberly R. Bennett +7 more
wiley +1 more source
Application of Haddon’s matrix in qualitative research methodology: an experience in burns epidemiology [PDF]
Background: Little has been done to investigate the application of injury specific qualitative research methods in the field of burn injuries. The aim of this study was to use an analytical tool (Haddon’s matrix) through qualitative research methods to ...
عرشی, شهنام +4 more
core +1 more source
Animals, 2020 Neutrophil extracellular traps (NETs) fight endometritis, and elastase (ELA), a protease found in NETs, might induce collagen type I (COL1) accumulation in equine endometrium. Metallopeptidases (MMPs) are involved in extracellular matrix balance. The aim
Ana Amaral +8 more
doaj +1 more source
Advanced Science, EarlyView.Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang +6 more
wiley +1 more source
Change in expression of extracellular matrix factor genes in 24
, 2014 Change in expression of extracellular matrix (ECM) factor genes 24 h following spinal cord injury at P28, subdivided into ECM, metallopeptidases, inhibitors, proteoglycans, laminins and integrins.
Jessie Truettner (575724) +13 more
core +1 more source
The Inhibition of Cathepsin G on Endometrial Explants With Endometrosis in the Mare
Frontiers in Veterinary Science, 2020 Although proteases found in neutrophil extracellular traps (NETs) have antimicrobial properties, they also stimulate collagen type 1 (COL1) production by the mare endometrium, contributing for the development of endometrosis.
Ana Amaral +10 more
doaj +1 more source
Advanced Science, EarlyView.ZBTB11 is identified as an oncogenic transcription factor that activates FBXO28 in breast cancer. FBXO28 promotes K48‐linked ubiquitination and degradation of MST1, suppressing Hippo signaling and enhancing epithelial–mesenchymal transition and metastasis. This transcription‐to‐ubiquitination cascade defines a prognostic biomarker axis and highlights a
An Xu +10 more
wiley +1 more source
Effect of the matrix behavior on the damage of ethylene–propylene glass fiber reinforced composite subjected to high strain rate tension [PDF]
, 2012 This study investigates the origin of the strain rate effect on the mechanical behavior of a discontinuous glass fiber reinforced ethylene–propylene copolymer (EPC) matrix composite.
FITOUSSI, Joseph +2 more
core +1 more source
Advanced Science, EarlyView.Resolution pharmacology is an emerging strategy to tackle inflammatory pathologies. Bioinspired meroterpenoids induce a lipid mediator class switch toward inflammation resolution in vitro and in vivo by targeting key nodes in lipid mediator biosynthesis and neutral lipid dynamics.
Lorenz Waltl +20 more
wiley +1 more source