Results 81 to 90 of about 19,663,610 (303)

Association of the matrix metalloproteinase-3 polymorphisms rs679620 and rs3025058 with ischemic stroke risk: a meta-analysis [PDF]

, 2018
Qi-Wei Zhang Department of Neurosurgery, The Affiliated Hospital of Jilin Medical University, Jilin, People’s Republic of China Purpose: The relationship of the matrix metalloproteinase-3 (MMP-3) polymorphisms rs679620 and rs3025058 with ischemic
Qi-Wei Zhang, Zhang Q
core   +1 more source

Dynamic Loading Regulates Meniscus‐Like Matrix Production in Human Mesenchymal Stromal Cell‐Seeded PET Scaffolds

Advanced Healthcare Materials, EarlyView.
Dynamic compression enhances mesenchymal stromal cell proliferation in nonwoven PET scaffolds under chondrogenic differentiation conditions and triggers mechanosensitive transcriptional programs associated with extracellular matrix remodeling. These findings highlight the potential of mechanically stimulated PET scaffolds as a promising platform for ...
Graciosa Quelhas Teixeira, Luisa de Roy, Anna‐Lotta Feldmeier, Mubashir Ahmad, Sofia Pilão, Maria Ahrens, Anita Ignatius, Carsten Linti, Andreas Martin Seitz   +8 more
wiley   +1 more source

Intracellular activation and processing of human disintegrin and metalloproteinase 19 (hADAM19) [PDF]

, 2003
Kang T. Intracellular activation and processing of human disintegrin and metalloproteinase 19 (hADAM19). Bielefeld (Germany): Bielefeld University; 2003.Adamalysin 19 (a disintegrin and metalloproteinase 19, ADAM19, or meltrin [beta]) is a plasma ...
Kang, Tiebang
core  

Matrix metalloproteinase 3 is a stromal marker for chicken ovarian cancer

Oncology Letters, 2011
Matrix metalloproteinases (MMPs) are involved in the degradation of the extracellular matrix and basement membranes. Due to this, MMPs have been thought to promote invasion and metastasis of cancer cells and angiogenesis in tumors. Even though the chicken is a useful animal model for studying human ovarian cancer, no reports exist of the MMP expression
Jin Won, Choi, Suzie E, Ahn, Deivendran, Rengaraj, Hee Won, Seo, Whasun, Lim, Gwonhwa, Song, Jae Yong, Han   +6 more
openaire   +3 more sources

Matrix Metalloproteinase 3 Is Present in the Cell Nucleus and Is Involved in Apoptosis [PDF]

The American Journal of Pathology, 2006
Matrix metalloproteinase (MMP)-3 is a protease involved in cancer progression and tissue remodeling. Using immunofluorescence and immunoelectron microscopy, we identified nuclear localization of MMP-3 in several cultured cell types and in human liver tissue sections.
Si-Tayeb, Karim, Monvoisin, Arnaud, Mazzocco, Claire, Lepreux, Sébastien, Decossas, Marion, Cubel, Gaëlle, Taras, Danièle, Blanc, Jean-Frédéric, Robinson, Derrick R, Rosenbaum, Jean   +9 more
openaire   +2 more sources

Blood–Brain Barrier Regulation: Evolving From Classic Strategies to Electrochemical Ion and Reactive Oxygen Species Control

Advanced Healthcare Materials, EarlyView.
Conventional therapies suffer from poor blood–brain barrier (BBB) penetration and disordered ion/reactive oxygen species (ROS) homeostasis, hindering precise neurological treatment. Electrochemical strategies achieve accurate spatiotemporal regulation of neural homeostasis.
Xiaokang Hu, Caiyu Liu, Meijun Pang, Zhiyuan Shi, Dong Ming, Xiuyun Liu   +5 more
wiley   +1 more source

The calpastatin-derived calpain inhibitor CP1B reduces mRNA expression of matrix metalloproteinase-2 and-9 and invasion by leukemic THP-1 cells [PDF]

, 2003
The ubiquitous proteases μ- and m-calpain are Ca2+-dependent cysteine endopeptidases. Besides involvement in a variety of physio(patho)logical processes, recent studies suggest a pivotal role of calpains in differentiation of hematopoietic cells and ...
Ries, C., Gil-Parrado, S., Jochum, M., Heidinger, M., Ruiz-Heinrich, L., Popp, O.   +5 more
core   +1 more source

Chemical Strategies for Multistimuli Responsive Dynamic Covalent Materials in Regenerative Medicine

Advanced Healthcare Materials, EarlyView.
Multistimuli responsive dynamic covalent materials integrate reversible chemistry with the complex chemical, mechanical, and biochemical cues of regenerative environments. This review highlights chemical strategies based on orthogonal dynamic bonds, multicomponent networks, and hierarchical architectures to regulate mechanics, degradation, and ...
Saurabh Joshi, Matthew B. Baker, Dominik Schauenburg   +2 more
wiley   +1 more source

Variants within the MMP3 gene are associated with achilles tendinopathy: possible interaction with the COL5A1 gene [PDF]

, 2009
Objectives: Sequence variation within the COL5A1 and TNC genes are known to associate with Achilles tendinopathy. The primary aim of this case-control genetic association study was to investigate whether variants within the matrix metalloproteinase 3 ...
Ribbans, William J, Raleigh, S M, Ribbans, W J, Smith, R K, Collins, M, Raleigh, Stuart M, Smith, R K W, Schwellnus, M P, van der Merwe, L, Ribbans, William J; id_orcid, Northampton   +10 more
core   +1 more source

Inhibition of Hippocampal Matrix Metalloproteinase-3 and -9 Disrupts Spatial Memory

Neural Plasticity, 2007
Memory consolidation requires synaptic reconfiguration dependent upon extracellular matrix (ECM) molecules interacting with cell adhesion molecules. Matrix metalloproteinase (MMP) activity is responsible for transient alterations in the ECM that may be
John W. Wright, Travis E. Brown, Joseph W. Harding   +2 more
doaj   +1 more source