Results 1 to 10 of about 19,511,098 (262)

Leptin and Pro-Inflammatory Stimuli Synergistically Upregulate MMP-1 and MMP-3 Secretion in Human Gingival Fibroblasts. [PDF]

PLoS ONE, 2016
Gingival fibroblast-mediated extracellular matrix remodelling is implicated in the pathogenesis of periodontitis, yet the stimuli that regulate this response are not fully understood.
Rachel C Williams, Andrew J Skelton, Stephen M Todryk, Andrew D Rowan, Philip M Preshaw, John J Taylor   +5 more
doaj   +3 more sources

Increased Matrix Metalloproteinase-2 and Matrix Metalloproteinase-3 Concentrations in Corneal Epithelium of Patients with Recurrent Corneal Erosions [PDF]

Journal of Ophthalmology, 2022
Purpose. To assess the role of selected matrix metalloproteinases in defective corneal re-epithelization in patients with recurrent corneal erosions. Subjects.
Katarzyna Jadczyk-Sorek, Wojciech Garczorz, Beata Bubała-Stachowicz, Tomasz Francuz, Ewa Mrukwa-Kominek   +4 more
doaj   +3 more sources

Identification of a novel role for matrix metalloproteinase-3 in the modulation of B cell responses in multiple sclerosis

Frontiers in Immunology, 2022
There has been a growing interest in the presence and role of B cell aggregates within the central nervous system of multiple sclerosis patients. However, very little is known about the expression profile of molecules associated with these aggregates and
Rittika Chunder, Rittika Chunder, Verena Schropp, Verena Schropp, Samir Jabari, Manuel Marzin, Sandra Amor, Stefanie Kuerten, Stefanie Kuerten   +8 more
doaj   +1 more source

Correlation of matrix metalloproteinase 3 and matrix metalloproteinase 9 levels with non-motor symptoms in patients with Parkinson’s disease

Frontiers in Aging Neuroscience, 2022
ObjectiveMatrix metalloproteinases (MMPs) are essential for tissue formation, neuronal network remodeling, and blood–brain barrier integrity. MMPs have been widely studied in acute brain diseases.
Chuan Ze Liu, Chuan Ze Liu, Da Shuai Guo, Da Shuai Guo, Jian Jun Ma, Jian Jun Ma, Jian Jun Ma, Lin Rui Dong, Lin Rui Dong, Qing Qing Chang, Qing Qing Chang, Hong Qi Yang, Hong Qi Yang, Hong Qi Yang, Ke Ke Liang, Ke Ke Liang, Xiao Huan Li, Xiao Huan Li, Da Wei Yang, Da Wei Yang, Yong Yan Fan, Yong Yan Fan, Qi Gu, Qi Gu, Qi Gu, Si Yuan Chen, Si Yuan Chen, Si Yuan Chen, Dong Sheng Li, Dong Sheng Li, Dong Sheng Li   +30 more
doaj   +1 more source

Matrix Metalloproteinase-3 but Not Matrix Metalloproteinase-9, Implicated in the Manifestation of Chronic Periodontitis

Reports of Biochemistry and Molecular Biology, 2023
Periodontal disease is an inflammatory condition affecting the tooth's supporting tissues, resulting in gradual loss of periodontal ligament (PDL), alveolar bone, and gum resorption. Neutrophil and monocyte/macrophage, destructive proteases like matrix metalloproteinase (MMP)-3 and MMP-9 play pivotal roles in such lesions in periodontitis.
Pouyan, Razavi, Seyed Abdolrahim, Rezaee, Salehe, Akhondian, Nastaran, Asgari, Kazem, Fatemi, Farnaz, Mohajertehran   +5 more
openaire   +2 more sources

Galectin-3 and matrix metalloproteinases 2 and 9 in peripheral blood of gastric cancer patients

Alʹmanah Kliničeskoj Mediciny, 2023
Background: High incidence of gastric cancer (GC), its aggressive clinical course, rapid tumor dissemination, low sensitivity to chemotherapy and lack of reliable laboratory diagnostic criteria urgently require a search for the most informative markers ...
Ekaterina A. Korotkova, Elena S. Gershtein, Ekaterina V. Samoilova, Irina O. Goryacheva, Aram P. Petrosyan, Natalia N. Zybina, Oleg O. Yanushevich, Ivan S. Stilidi, Nikolay E. Kushlinskii   +8 more
doaj   +1 more source

Role of Gene Polymorphisms of Matrix Metalloproteinases-2, -3 and -13 in the Development of Coronary Artery Atherosclerosis in Patients with Primary Polyosteoarthrosis

Архивъ внутренней медицины, 2020
The aim of the research. To assess the influence of polymorphisms of the matrix metalloproteinase genes — 2 (rs2285053), — 3 (rs3025058), and — 13 (rs2252070) on the development of coronary atherosclerosis in patients with primary osteoarthritis ...
O. O. Portyannikova, E. N. Romanova, A. V. Govorin, S. M. Tsvinger   +3 more
doaj   +1 more source

Matrix Metalloproteinase 3 Polymorphism [PDF]

Clinical Cancer Research, 2004
Abstract Purpose: Treatment of head and neck cancer often associates different therapeutic modalities, including surgery, radiotherapy, and chemotherapy. In an attempt to optimize therapeutics, the identification of molecular markers linked to response to chemotherapy remains important.
Hélène Blons, Sophie Gad, Franck Zinzindohoué, Isabelle Manière, Janie Beauregard, David Tregouet, Daniel Brasnu, Philippe Beaune, Ollivier Laccourreye, Pierre Laurent-Puig   +9 more
openaire   +1 more source

Impaired Expression of Membrane Type-2 and Type-3 Matrix Metalloproteinases in Endometriosis but Not in Adenomyosis

Diagnostics, 2022
Matrix metalloproteinases (MMPs) play an important role in menstruation and endometriosis; however, the membrane-type matrix metalloproteinases (MT-MMPs) are not well studied in endometriosis and adenomyosis.
Jane B. Maoga, Muhammad A. Riaz, Agnes N. Mwaura, Georgios Scheiner-Bobis, Ezekiel Mecha, Charles O. A. Omwandho, Ivo Meinhold-Heerlein, Lutz Konrad   +7 more
doaj   +1 more source

Matrix Metalloproteinase 3 Is a Mediator of Pulmonary Fibrosis [PDF]

The American Journal of Pathology, 2011
Idiopathic pulmonary fibrosis (IPF) may be triggered by epithelial injury that results in aberrant production of growth factors, cytokines, and proteinases, leading to proliferation of myofibroblasts, excess deposition of collagen, and destruction of the lung architecture. The precise mechanisms and key signaling mediators responsible for this aberrant
Cory M, Yamashita, Lior, Dolgonos, Rachel L, Zemans, Scott K, Young, Jennifer, Robertson, Natalie, Briones, Tomoko, Suzuki, Megan N, Campbell, Jack, Gauldie, Derek C, Radisky, David W H, Riches, Guoying, Yu, Naftali, Kaminski, Christopher A G, McCulloch, Gregory P, Downey   +14 more
openaire   +2 more sources