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Matrix metalloproteinases‐9 in preterm and term human parturition
The Journal of Maternal‐Fetal Medicine, 1999Spontaneous rupture of the fetal membranes occurs after the commencement of labor in 90% of cases. Recent evidence indicates that the process of parturition requires not only an increase in myometrial contractility and cervical ripening, but also degradation of extracellular matrix in fetal membranes (i.e., leakage of fibronectin into cervico-vaginal ...
ATHAYDE N +10 more
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DNA and Cell Biology, 2012
Altered matrix metalloproteinases (MMPs) levels are involved in cardiovascular diseases and increased MMP-9 levels enhance the cardiovascular risk in apparently healthy subjects. We investigated the effects of MMP-9 gene polymorphisms and haplotypes on the circulating MMP-9 levels in healthy black subjects and the effects of an MMP-2 polymorphism on ...
Ingrid F, Metzger +3 more
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Altered matrix metalloproteinases (MMPs) levels are involved in cardiovascular diseases and increased MMP-9 levels enhance the cardiovascular risk in apparently healthy subjects. We investigated the effects of MMP-9 gene polymorphisms and haplotypes on the circulating MMP-9 levels in healthy black subjects and the effects of an MMP-2 polymorphism on ...
Ingrid F, Metzger +3 more
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Matrix metalloproteinase-9 and osteoporosis
2023Introduction: Matrix metalloproteinases (MMPs) are a family of zinc-dependent proteolytic enzymes involved in the degradation of extracellular matrix (ECM) components. The overexpression and increased activity of MMPs is observed in many physiological and pathological processes, including estrogen deficiency osteoporosis.
Grigoryan, Armine V. +4 more
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The role of matrix metalloproteinase-9 in dementia
Neuroscience Letters, 2003Neurofibrillary tangles and senile plaques, constituted of extracellular amyloid deposits (Abeta), are the two defining pathological hallmarks of Alzheimer's disease (AD). Inhibiting the synthesis or aggregation of Abeta or increasing its clearance may reduce the detrimental effects of this peptide and consequently improve cognitive functions in ...
Nicole, Helbecque +3 more
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Matrix Metalloproteinase-9 and Airway Remodeling in Asthma
Current Drug Target -Inflammation & Allergy, 2005Airway remodeling is a major change responsible for irreversible asthmatic airflow restriction. The Th-2 cytokines-dominant eosinophilic inflammatory mechanism cannot fully explain the progressive subepithelial fibrosis and structural changes in the extracellular matrix (ECM).
Hiroyuki, Ohbayashi, Kaoru, Shimokata
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Matrix metalloproteinase—9 concentration after spontaneous intracerebral hemorrhage
Journal of Neurosurgery, 2003Object. Matrix metalloproteinases (MMPs) are overexpressed in the presence of some neurological diseases in which blood—brain barrier disruption exists. The authors investigated the MMP-9 concentration in patients after acute intracerebral hemorrhage (ICH) and its relation to perihematomal edema (PHE). Methods.
Sònia, Abilleira +5 more
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The biofilm matrix: multitasking in a shared space
Nature Reviews Microbiology, 2022Hans-Curt Flemming +2 more
exaly