Results 111 to 120 of about 2,335,867 (359)
The Structural Biology and Critical Evaluation of Bacterial Proteases as Targets in New Drug Design [PDF]
arXiv, 2014 Bacteria produce a range of proteolytic enzymes, for which a number human equivalent or structurally similar examples exist and the primary focus of this study was to analyse the published literature to find proteolytic enzymes, specifically endoproteses and to examine the similarity in the substrates that they act on so as to predict a suitable ...
arxiv
Spatially Controlled 3‐D Multiplexed Aptamer Patterning in Hydrogels
Advanced Materials Interfaces, EarlyView.A hydrogel platform based on norbornene‐functionalized polyvinyl alcohol enables high‐resolution, 3‐D multiplexed patterning of DNA aptamers via two‐photon polymerization. Two distinct aptamers are covalently immobilized with single micron‐scale precision across the x, y, and z dimensions.
Kevin Roost +9 more
wiley +1 more source
Tuning the Morphological Properties of Granular Hydrogels to Control Lymphatic Capillary Formation
Advanced Materials Interfaces, EarlyView.Tuning the morphological properties of granular hydrogels is essential to generate robust lymphatic capillary networks that express key lymphatic gene and protein markers. The study demonstrates that 3D in vitro lymphatic tube formation is controlled not by the mechanical properties of the gel, but by the pore size and topology (periodicity) of the gel
Daniel Montes +7 more
wiley +1 more source
Progress in Surface Plasmon and Other Resonance Biosensors for Biomedical Applications
Advanced Materials Technologies, EarlyView.This is the shortened version: Recent advancements in surface plasmon resonance and other optical resonance biosensors for biomedical applications are presented. Advanced sensing strategies are examined for the detection of diverse analytes, integration of nanomaterials and machine learning, and emerging nonplasmonic modes like guided mode resonance ...
Faten Bashar Kamal Eddin +8 more
wiley +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 2000 Membrane-type matrix metalloproteinase I (MT1-MMP)-deficient mice were found to have severe defects in skeletal development and angiogenesis. The craniofacial, axial, and appendicular skeletons were severely affected, leading to a short and domed skull ...
Zhongjun Zhou +8 more
semanticscholar +1 more source
Genes for extracellular-matrix-degrading metalloproteinases and their inhibitor, TIMP, are expressed during early mammalian development. [PDF]
, 1989 Christine Brenner +4 more
openalex +1 more source
A hydroxamic acid-methacrylated collagen conjugate for the modulation of inflammation-related MMP upregulation [PDF]
Journal of Materials Chemistry B 2018, 2018 Medical devices with matrix metalloproteinase (MMP) modulating functionality are highly desirable to restore tissue homeostasis in critical inflammation states, such as chronic wounds, rotator cuff tears and cancer. The introduction of MMP-modulating functionality in such devices is typically achieved via loading of either rapidly-diffusing chelating ...
arxiv
Modern Strategies in Wound Healing: The Rise of Bacterial Cellulose Dressings
Advanced Therapeutics, EarlyView.Bacterial cellulose (BC)‐based wound dressings combine high water retention, biocompatibility, and mechanical strength to support wound healing. This review highlights advanced functionalization strategies and fabrication techniques that enhance BC's therapeutic performance, establishing it as a promising material for next‐generation wound care ...
Elif Naz Gürsoy +4 more
wiley +1 more source
Matrix Metalloproteinase-Induced Epithelial-Mesenchymal Transition in Breast Cancer
Journal of mammary gland biology and neoplasia, 2010 Matrix metalloproteinases (MMPs) degrade and modify the extracellular matrix (ECM) as well as cell-ECM and cell-cell contacts, facilitating detachment of epithelial cells from the surrounding tissue.
E. Radisky, D. Radisky
semanticscholar +1 more source
Kaohsiung Journal of Medical Sciences, 2013 Matrix metalloproteinase (MMP) is involved in the upper airway remodeling process. We hypothesized that MMP had an additive effect on the formation of recurrent nasal polyp.
Ling-Feng Wang +4 more
doaj +1 more source