Results 131 to 140 of about 155,893 (261)

Tissue‐Specific and Spatially Dependent Metabolic Signatures Perturbed by Injury in Male and Female Mice

Arthritis &Rheumatology, EarlyView.
Objective Osteoarthritis, the leading cause of disability worldwide, disproportionately affects women, yet sex remains an overlooked determinant. This disparity stems from sex‐specific differences in injury susceptibility—a major risk factor for disease.
Hope D. Welhaven, Avery H. Welfley, Priyanka P. Brahmachary, Mark Greenwood, Donald F. Smith, Brian Bothner, Ronald K. June   +6 more
wiley   +1 more source

Matrix metalloproteinase activation and TNF upregulation characterize the sclerotic phase of aortic valve disease. [PDF]

Br J Biomed Sci
Chan-Delgado E, Lerma C, Echeverría JC, Toledo A, Torres-Arellano JM, Infante O, Bojalil R, Cossío-Aranda JE, Ávila-Vanzzini N, Amezcua-Guerra LM, Springall R.   +10 more
europepmc   +1 more source

Prolotherapy in the Treatment of Knee Osteoarthritis: How to Perform

Arthroscopy Techniques, EarlyView.
Abstract The conservative treatment of knee osteoarthritis is a challenge; since it has no cure, many patients do not want or cannot undergo surgical procedures. Among the various options, we have injectable therapies, especially the so‐called “regenerative,” such as the use of hyaluronic acid, orthobiologicals, and prolotherapy. In the latter, its use
José L. Rocha de Faria, Fabiana Alves C. Menegassi, Sandra T. N. Minamoto, Guilherme Blois V. Pereira, Fábio Henrique P. Videira, Diego G. Severgnine, Caio Gomes de Lima, José Paulo G. Aramburu Filho, Geraldo da R. Motta, João Antônio M. Guimarães, Ronaldo José Faria C. do Amaral, Bianca Gutfilen, Sergio Augusto L. de Souza, Zartur José B. Menegassi   +13 more
wiley   +1 more source

Unravelling the Contribution of Matrix Metalloproteinase-3 Genotype-Phenotype to Pterygium Risk. [PDF]

Cancer Genomics Proteomics
Chen HC, Hsia NY, Tsai CL, Hsia TC, Hu PS, Wang YC, Shih HY, Chang WS, Lin JC, Bau DT, Tsai CW.   +10 more
europepmc   +1 more source

From anthelmintic to neuro‐oncology: A systematic review of mebendazole repurposing for brain tumour therapy

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Mebendazole (MBZ), a benzimidazole anthelmintic with established clinical use, has emerged as a repurposing candidate for primary brain tumours due to its multimodal anticancer actions and central nervous system penetrance. This systematic review synthesizes preclinical and clinical evidence evaluating MBZ's efficacy, mechanisms of action ...
Ciara B. Blum, Milli McMenamin, Tessa Khoo, John M. Edwin, Prathibha Jose, Liam A. O’Callaghan   +5 more
wiley   +1 more source

New opportunities for bioscaffold‐enabled spinal cord injury repair

BMEMat, EarlyView.
Schematic illustration of bioscaffolds for spinal cord injury repair. We summarize the effects of bioscaffold properties on SCI repair, highlight different types of bioscaffolds, various fabrication strategies, and in vivo transformations for the clinical development of SCI‐repairing bioscaffolds.
Xiaoqing Qi, Yicheng Fu, Zhaoliang Su, Li Li, Subrata Chakrabarti, Peng Li, Yilun Wu, Fang Liu, Teng Gao, Zhifeng Dong, Lei Liu, Pei Cao   +11 more
wiley   +1 more source

Elevated serum levels of interleukin-11 and matrix metalloproteinase-9 in myalgic encephalomyelitis/chronic fatigue syndrome. [PDF]

Front Immunol
Chinnappan B, Kempuraj D, Aenlle KK, Middleton A, Day KS, Kothuru SP, Joshi RS, Klimas NG, Theoharides TC.   +8 more
europepmc   +1 more source

Cold atmospheric plasma‐mediated tumor microenvironment remodeling for cancer treatment

BMEMat, EarlyView.
Schematic presentation of CAP‐mediated TME remodeling. This review summarizes recent efforts in cold atmospheric plasma (CAP) application in cancer treatment, highlighting the anticancer potential of CAP, molecular mechanisms, and future perspectives for further improvement and clinical translation.
Israr Khan, Qiujie Fang, Cao Fei, Ziyuan Wang, Zhaowei Chen, Guojun Chen, Zhiming Xu, Shu Xu, Zhitong Chen   +8 more
wiley   +1 more source

Cumulative evidence for associations between matrix metalloproteinase-1, -3 and -8 variants and cancer risk. [PDF]

Oncol Lett
Xu S, Liu X, Huang C.
europepmc   +1 more source

Advancing design strategies in smart stimulus‐responsive liposomes for drug release and nanomedicine

BMEMat, EarlyView.
Schematic illustration of stimulus‐responsive liposomes designed for controlled drug release and nanomedicine. The innermost circle represents different liposomal structures, including unilamellar, multilamellar, and multivesicular liposomes. The middle layer illustrates the responsive phospholipid components.
Yuchen Guo, Nan Li, Daiwei Zhang, Jingya Gu, Zhihuan Liao, Zihao Teng, Xiangfu Du, Peter S. Timashev, Shipeng Chen, Shuaidong Huo   +9 more
wiley   +1 more source