Results 151 to 160 of about 157,261 (261)

Effects of antihypertensive therapy on matrix metalloproteinase-9 levels in controlled hypertensive patients. [PDF]

BMC Cardiovasc Disord
Vilela-Martin JF, Minari TP, da Silva MAV, da Silva Lopes V, de Oliveira KA, de Almeida MA, Lacchini R, Tanus-Santos JE, Moreno H, Yugar-Toledo JC, Cosenso-Martin LN.   +10 more
europepmc   +1 more source

Cytokine Pathways Driving Diverse Tissue Pathologies in Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Rheumatoid arthritis (RA) is a complex systemic disorder characterized primarily by articular inflammation and destruction with associated functional loss and reduced quality of life. RA is also associated with extra‐articular disease, such as that of the lung, with potentially devastating clinical consequences. The critical importance of comorbidities,
Aurelie Najm, Lyn D. Ferguson, Iain B. McInnes   +2 more
wiley   +1 more source

Myocardial Matrix Metalloproteinase 3 Protein Expression in Ischemic Heart Failure. [PDF]

Int J Mol Sci
Siratavičiūtė V, Pangonytė D, Lesauskaitė V, Utkienė L, Jusienė L, Marcinkevičienė J, Kuprytė M, Gečys D, Patamsytė V, Stanionienė Z, Radikė R.   +10 more
europepmc   +1 more source

Arthroscopic Assisted Turf Toe Reconstruction With Knotless Suture Anchors and Suture Tape Augmentation

Arthroscopy Techniques, EarlyView.
Abstract Turf toe is a hallux metatarsophalangeal joint (MTPJ) injury seen in sports like football and soccer where the foot experiences axial load while fixed to the ground with the great toe hyperextended at the MTPJ. Depending on severity, turf toe can be quite devastating in athletes and can require operative intervention.
Nicholas K. Pappa, Kyle S. Ardavanis, Tobin Eckel, Kevin D. Martin   +3 more
wiley   +1 more source

Matrix Metalloproteinase-13 Is an Unfavorable Prognostic Factor in Chordoma by Digesting Growth Inhibitory Collagens. [PDF]

Cancer Med
Oishi Y, Kawaai K, Tamura R, Kuroda Y, Noji S, Toda M, Matsuo K.   +6 more
europepmc   +1 more source

From anthelmintic to neuro‐oncology: A systematic review of mebendazole repurposing for brain tumour therapy

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Mebendazole (MBZ), a benzimidazole anthelmintic with established clinical use, has emerged as a repurposing candidate for primary brain tumours due to its multimodal anticancer actions and central nervous system penetrance. This systematic review synthesizes preclinical and clinical evidence evaluating MBZ's efficacy, mechanisms of action ...
Ciara B. Blum, Milli McMenamin, Tessa Khoo, John M. Edwin, Prathibha Jose, Liam A. O’Callaghan   +5 more
wiley   +1 more source

Matrix metalloproteinase-9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells. [PDF]

FEBS Open Bio
Strauel C, Bennett S, Ehlinger N, Cook N, Marvin K, Lines CL, Reyes S, Kirby B, Ellerbroek SM.   +8 more
europepmc   +1 more source

Purification of Advanced Therapeutics by Flow‐Through Pseudo‐Affinity Chromatography: Bi‐Specific mABs, Fc Fusion Proteins, and Adeno‐Associated Viruses

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Modern biopharmaceutical manufacturing requires purification platforms capable of processing structurally and functionally diverse products while addressing the challenge of removing persistent and high‐risk host cell proteins (HCPs).
Wenning Chu, Eduardo Barbieri, Arianna Minzoni, Shriarjun Shastry, Jacob P. LeBarre, Qingbo Shu, Taufika Williams, Xuanwen Li, Divya Chandra, Xuankuo Xu, Jerome Bill, David Roush, Joseph Taris, Patrick Gilbert, Andre Kiesewetter, Oliver Rammo, Michael Schulte, Christopher Major, Trina Mouchahoir, Steven Cramer, Cristiana Boi, Ruben G. Carbonell, Abraham Lenhoff, Stefano Menegatti   +23 more
wiley   +1 more source

Matrix metalloproteinase expression in basal cell carcinoma, squamous carcinoma, and melanoma: diagnostic and prognostic potential. [PDF]

Front Oncol
Spatola GF, Pitruzzella A, Listro AG, Valenti C, Scalisi M, Milia F, Listro P, Zingales F, Ferranti GM, Listro M, Belmonte B, Picone D, Intili G, Uzzo ML.   +13 more
europepmc   +1 more source

2D copper nanozyme patches facilitate bone regeneration via interfacial modulation of osteoclast‐osteoblast dynamics

BMEMat, EarlyView.
This study develops a nano‐enzyme patch (ezPatch) targeting bone interfaces. Utilizing ligand‐to‐metal charge transfer (LMCT) catalysis and bone‐targeting ligands on copper nanosheets, ezPatch simultaneously scavenges reactive oxygen species (ROS) and generates oxygen in situ at bone‐losing sites.
Yi Chen, Haoyue Hu, Danyang Wang, Ying Wang, Zhibang Li, Xiaoyi Liu, Yandi Zhang, Junkun Feng, Weiwei Zhao, Kai Li, Qi‐Zhi Zhong, Shaohua Ge, Jianhua Li   +12 more
wiley   +1 more source