Results 171 to 180 of about 155,893 (261)

Examining the Role of Matrix Metalloproteinase-2 and MicroRNAs Regulation in Breast Cancer. [PDF]

Breast J
Vand Beilankouhi EA, Kheradi N, Vaez-Gharamaleki Y, Roshani S, Abbasi S, Safaralizadeh R, Valilo M.   +6 more
europepmc   +1 more source

The Serotonin 2B (5‐HT2B) Receptor: A Narrative Review of Preclinical and Clinical Evidence on the Safety Considerations and Therapeutic Potential for the Treatment of Depression

Clinical Pharmacology &Therapeutics, EarlyView.
Major depressive disorder (MDD) and treatment‐resistant depression (TRD) remain leading causes of disability, providing the impetus for receptor‐level treatment strategies beyond monoamine reuptake. The serotonin 5‐HT2B receptor (5‐HT2BR) is uniquely positioned at the interface of central‐antidepressant mechanisms and peripheral cardiac risks.
Gia Han Le, Sabrina Wong, Danica E. Johnson, Diana K. Orsini, Yang Jing Zheng, Kayla M. Teopiz, Christine E. Dri, Joshua D. Rosenblat, Roger S. McIntyre   +8 more
wiley   +1 more source

Statin-loaded carbonated hydroxyapatite nanoemulsion controls matrix metalloproteinase-1 activity to enhance post-orthodontic stability in rats. [PDF]

J Appl Oral Sci
Alhasyimi AA, Rosyida NF, Pudyani PS.
europepmc   +1 more source

Droplet microfluidics: Enabling the tailored fabrication of hydrogel particles

Droplet, EarlyView.
Droplet microfluidics enables precise, versatile fabrication of hydrogel particles with controlled size, composition, and structure. This review summarizes fundamental principles, engineering strategies, and emerging applications, providing a framework for advancing microfluidic hydrogel technologies.
Zhongqiao Gan, Xu Hou
wiley   +1 more source

Comparative evaluation of the resin-dentin interface using different matrix metalloproteinase inhibitors: A confocal laser scanning microscopic study. [PDF]

J Conserv Dent Endod
Bahekar A, Tandale A, Kasat V, Balani M, Takbhate B, Bangar R.   +5 more
europepmc   +1 more source

Analysis and Characterization of Kisspeptin and Its Analogues in Serum and Urine Samples by Liquid Chromatography–High‐Resolution Mass Spectrometry for Doping Control Purposes

Drug Testing and Analysis, EarlyView.
Sensitive LC‐HRMS methods were established for the detection of kisspeptin and its analogues in serum and urine, alongside their analytical and metabolic characterization. Stability studies were conducted in serum, plasma, and urine, highlighting the importance of appropriate sample handling for reliable anti‐doping analysis.
Sophia Krombholz, Linus Korsmeier, Andreas Thomas, Mario Thevis   +3 more
wiley   +1 more source

Matrix Metalloproteinase Inhibitors and Their Potential Clinical Application in Periodontitis. [PDF]

Diseases
Mendoza-Juárez D, Sánchez-Gutiérrez M, Izquierdo-Vega AJ, Madrigal-Santillán EO, Velázquez-González C, Izquierdo-Vega JA.   +5 more
europepmc   +1 more source

Robinow syndrome DVL1 variants disrupt morphogenesis and appendage formation in a Drosophila disease model

Developmental Dynamics, EarlyView.
Abstract Background Robinow syndrome is a rare developmental syndrome caused by variants in genes in Wnt signaling pathways. We previously showed that expression of patient variants in Dishevelled 1 (DVL1) in Drosophila and chicken models disrupts the balance of canonical and non‐canonical Wnt signaling.
Gamze Akarsu, Katja R. MacCharles, Kenneth Kin Lam Wong, Joy M. Richman, Esther M. Verheyen   +4 more
wiley   +1 more source

Tear matrix metalloproteinase 9 immunoassay positivity reflects the severity of conjunctivochalasis. [PDF]

Sci Rep
Lee J, Bang SP, Lee J, Shim KY, Jun JH.
europepmc   +1 more source

Secretopathies emerge as a new class of neurocristopathies

Developmental Dynamics, EarlyView.
Abstract Neural crest cells are a transient embryonic population of cells that give rise to a wide range of structures, including craniofacial cartilage and bone, peripheral neurons and glia, as well as components of the cardiac outflow tract, among others.
Amanda Teixeira, Cassandra Millet‐Boureima, Joshua A. Moore, Loydie A. Jerome‐Majewska   +3 more
wiley   +1 more source