Results 171 to 180 of about 2,335,867 (359)

Cartilage‐Penetrating Framework Nucleic Acid Nanoparticles Ameliorate Osteoarthritis by Promoting Drug Delivery and Chondrocyte Uptake

open access: yesAdvanced Science, EarlyView.
Based on the poor cartilage penetration of tFNA, a novel tFNA‐2WL with excellent cartilage permeability and perfect chondrocyte endocytosis properties is designed and fabricated. As a result, tFNA‐2WL has a nearly seven‐fold increase in the penetration depth into the cartilage, with the same excellent cell entry properties as tFNA.
Kui Huang   +9 more
wiley   +1 more source

Highly Stretchable, Self‐Healable, and Conductive Gelatin Methacryloyl Hydrogel for Long‐Lasting Wearable Tactile Sensors

open access: yesAdvanced Science, EarlyView.
Gelatin methacryloyl hydrogel, which possesses high stretchability, tensile strength, toughness, and autonomous self‐healing capability at room temperature, is developed through the introduction of interpenetrating networks, hierarchical hydrogen bonds (weak and strong H‐bonds), and borate ester bonds.
Zhikang Li   +14 more
wiley   +1 more source

Matrix metalloproteinase collagenolysis in health and disease.

open access: yesBiochimica et biophysica acta. Molecular cell research, 2017
S. Amar, Lyndsay Smith, G. Fields
semanticscholar   +1 more source

Targeted Intervention Strategies for Maternal–Offspring Transmission of Christensenellaceae in Pigs via a Deep Learning Model

open access: yesAdvanced Science, EarlyView.
This study deciphers maternal‐driven microbial transmission in pigs using a deep learning model (maternal–offspring microbial transmission model), identifying Christensenellaceae R‐7 group as a key transmitted taxon. Filtered galacto‐oligosaccharides‐targeted Christensenellaceae R‐7 group alters offspring microbial functions via maternal ...
Haibo Shen   +9 more
wiley   +1 more source

Inhibition of Heat Shock Protein 90β by Catalpol: A Potential Therapeutic Approach for Alleviating Inflammation‐Induced Cartilage Injuries in Osteoarthritis

open access: yesAdvanced Science, EarlyView.
The schematic diagram delineates the chondroprotective effects of Ca‐bMSN in OA models. The upper portion of the diagram depicts the synthesis process of Ca‐bMSN. The lower section illustrates the post‐injection of Ca‐bMSN in joint cavity, catalpol released and subsequently mediates the reduction of oxidative stress, ECM catabolism, apoptosis, and ...
Zhenwei Zhou   +14 more
wiley   +1 more source

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