Results 191 to 200 of about 2,315,187 (340)

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

The hemopexin domain of matrix metalloproteinase-9 attenuates lipopolysaccharide-induced interleukin-6 secretion in liver. [PDF]

Sci Rep
Chien YT, Liao YH, Chong XW, Hsu MC, Chiu CH, Huang C.   +5 more
europepmc   +1 more source

Effects of Matrix Metalloproteinase-9 Gene Knock-Out on the Proteolysis of Blood–Brain Barrier and White Matter Components after Cerebral Ischemia

Journal of Neuroscience, 2001
M. Asahi, Xiaoying Wang, Tatsuro Mori, T. Sumii, Jae‐Chang Jung, M. A. Moskowitz, M. E. Fini, E. Lo   +7 more
semanticscholar   +1 more source

Gene polymorphism of matrix metalloproteinase -1 in chronic periapical lesions and acute odontogenic infection [PDF]

, 2014
Biljana Evrosimovska, Cena Dimova
openalex  

IL‐4/STAT6‐signaling Influences Local Inflammation and Regeneration Processes During Acute Pancreatitis and Promotes Fibrosis by a Direct Activation of Pancreatic Fibroblasts During Chronic Pancreatitis

Advanced Science, EarlyView.
IL‐4/IL‐13/STAT6 signaling plays a crucial for the suppression of pro‐inflammation during acute pancreatitis and supports acinar cell regeneration but has only minor impact on fibrogenesis during chronic form of the disease. IL‐4/IL‐13 induce the expression of certain collagens directly in pancreatic fibroblasts via STAT6 activation, whereas ...
ElSheikh H, Salvers A, Piesker J, Buchholz S, Lange R, Ameling S, Steil L, Hammer E, Homuth G, Völker U, Bröker BM, Weiss FU, Sendler M, Glaubitz J   +13 more
wiley   +1 more source

Horizontal transfer of matrix metalloproteinase genes links early animal and microbial evolution. [PDF]

Biol Direct
Parsons C, Fournier GP.
europepmc   +1 more source

MicroRNA 21 Promotes Glioma Invasion by Targeting Matrix Metalloproteinase Regulators

Molecular and Cellular Biology, 2008
Galina Gabriely, T. Wurdinger, S. Kesari, Christine Esau, J. Burchard, P. Linsley, Anna M. Krichevsky   +6 more
semanticscholar   +1 more source

Preface — Matrix metalloproteinases

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2017
openaire   +2 more sources

Collagen Degradation in Aged/Photodamaged Skin In Vivo and After Exposure to Matrix Metalloproteinase-1 In Vitro [PDF]

, 2003
Suzanne Fligiel, James Varani, Subhash C. Datta, Sewon Kang, Gary J. Fisher, John J. Voorhees   +5 more
openalex   +1 more source

Stimuli‐Responsive Supramolecular Biomaterials for Cancer Theranostics

Advanced Science, EarlyView.
The ultimate goal of cancer theranostics is to get imaging agents and therapeutic cargo to tumor sites when and where they are required. “Smart” systems should be developed. This review discusses the characteristics of physiological stimuli, types and action modes of external stimuli, construction approaches and working principles, as well as ...
Wenting Hu, Binglin Ye, Guocan Yu, Feihe Huang, Zhengwei Mao   +4 more
wiley   +1 more source