Results 21 to 30 of about 2,335,867 (359)
Leptin and Pro-Inflammatory Stimuli Synergistically Upregulate MMP-1 and MMP-3 Secretion in Human Gingival Fibroblasts. [PDF]
PLoS ONE, 2016 Gingival fibroblast-mediated extracellular matrix remodelling is implicated in the pathogenesis of periodontitis, yet the stimuli that regulate this response are not fully understood.
Rachel C Williams +5 more
doaj +1 more source
The Rebirth of Matrix Metalloproteinase Inhibitors: Moving Beyond the Dogma
Cells, 2019 The pursuit of matrix metalloproteinase (MMP) inhibitors began in earnest over three decades ago. Initial clinical trials were disappointing, resulting in a negative view of MMPs as therapeutic targets.
G. Fields
semanticscholar +1 more source
Matrix Metalloproteinase-9 (MMP-9) as a Cancer Biomarker and MMP-9 Biosensors: Recent Advances
Italian National Conference on Sensors, 2018 As one of the most widely investigated matrix metalloproteinases (MMPs), MMP-9 is a significant protease which plays vital roles in many biological processes. MMP-9 can cleave many extracellular matrix (ECM) proteins to regulate ECM remodeling.
Hao-Hsiu Huang
semanticscholar +1 more source
The role of MMP-2 and MMP-9 in the metastasis and development of hypopharyngeal carcinoma
Brazilian Journal of Otorhinolaryngology, 2021 Introduction: The role of matrix metalloproteinase-2 and 9 in the metastasis and development of hypopharyngeal carcinoma has not been clarified. Objectives: To observe the relationship between matrix metalloproteinase-2, matrix metalloproteinase-9 and ...
Zhe Song +5 more
doaj
Клінічна хірургія, 2022 Objective. To improve the results of treatment in patients, suffering insufficiency of sutures of intestinal anastomoses, using analysis of rate in the genes polymorphous variants of the matrix metalloproteinase Type 2 (C-1306 →T) and the tissue ...
O. Yu. Usenko, Ya. Yu. Voitiv
doaj +1 more source
Protease-sensitive atelocollagen hydrogels promote healing in a diabetic wound model [PDF]
Journal of Materials Chemistry B 2016, 2016 The design of exudate-managing wound dressings is an established route to accelerated healing, although such design remains a challenge from material and manufacturing standpoints. Aiming towards the clinical translation of knowledge gained in vitro with highly swollen rat tail collagen hydrogels, this study investigated the healing capability in a ...
arxiv +1 more source
Facial structure of matrix convex sets [PDF]
J. Funct. Anal. 283 (2022) 109601, 55pp, 2021 This article investigates the notions of exposed points and (exposed) faces in the matrix convex setting. Matrix exposed points in finite dimensions were first defined by Kriel in 2019. Here this notion is extended to matrix convex sets in infinite-dimensional vector spaces.
arxiv +1 more source
Cell Transplantation, 2019 Emerging evidence demonstrates that dysregulation of circular RNA is linked to tumorigenesis and aggressive progression. However, its role in oral squamous cell carcinoma remains largely uncharacterized.
Bing Xia +4 more
doaj +1 more source
Role of Matrix Metalloproteinase-2 in Eosinophil-Mediated Airway Remodeling
Frontiers in Immunology, 2018 Airway remodeling is responsible for the progressive decline of lung function in bronchial asthma. Matrix metalloproteinase-2 and fibroblast-to-myofibroblast transition are involved in tissue remodeling.
Yu Kuwabara +10 more
doaj +1 more source
ASAP-SML: An Antibody Sequence Analysis Pipeline Using Statistical Testing and Machine Learning [PDF]
, 2020 Antibodies are capable of potently and specifically binding individual antigens and, in some cases, disrupting their functions. The key challenge in generating antibody-based inhibitors is the lack of fundamental information relating sequences of antibodies to their unique properties as inhibitors.
arxiv +1 more source