Results 11 to 20 of about 157,261 (261)

Protective Role of Matrix Metalloproteinase-2 in Allergic Bronchial Asthma

Frontiers in Immunology, 2019
Inflammation, reversible obstruction, and hyperresponsiveness of the airways are characteristic findings of bronchial asthma. Several evidence has demonstrated the involvement of matrix metalloproteinase-2 in allergic airway inflammation.
Yoshinori Takahashi, Tetsu Kobayashi, Corina N. D'Alessandro-Gabazza, Masaaki Toda, Kentaro Fujiwara, Tomohito Okano, Hajime Fujimoto, Kentaro Asayama, Atsuro Takeshita, Atsuro Takeshita, Taro Yasuma, Taro Yasuma, Kota Nishihama, Ryo Inoue, Liqiang Qin, Yoshiyuki Takei, Osamu Taguchi, Esteban C. Gabazza   +17 more
doaj   +1 more source

Leptin and Pro-Inflammatory Stimuli Synergistically Upregulate MMP-1 and MMP-3 Secretion in Human Gingival Fibroblasts. [PDF]

PLoS ONE, 2016
Gingival fibroblast-mediated extracellular matrix remodelling is implicated in the pathogenesis of periodontitis, yet the stimuli that regulate this response are not fully understood.
Rachel C Williams, Andrew J Skelton, Stephen M Todryk, Andrew D Rowan, Philip M Preshaw, John J Taylor   +5 more
doaj   +1 more source

Matrix Metalloproteinases: A Review [PDF]

Critical Reviews in Oral Biology & Medicine, 1993
Matrix metalloproteinases (MMPs) are a family of nine or more highly homologous Zn++endopeptidases that collectively cleave most if not all of the constituents of the extracellular matrix. The present review discusses in detail the primary structures and the overlapping yet distinct substrate specificities of MMPs as well as the mode of activation of ...
H, Birkedal-Hansen, W G, Moore, M K, Bodden, L J, Windsor, B, Birkedal-Hansen, A, DeCarlo, J A, Engler   +6 more
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A circular RNA derived from MMP9 facilitates oral squamous cell carcinoma metastasis through regulation of MMP9 mRNA stability

Cell Transplantation, 2019
Emerging evidence demonstrates that dysregulation of circular RNA is linked to tumorigenesis and aggressive progression. However, its role in oral squamous cell carcinoma remains largely uncharacterized.
Bing Xia, Tao Hong, Xin He, Xinlan Hu, Yongbo Gao   +4 more
doaj   +1 more source

Role of Matrix Metalloproteinase-2 in Eosinophil-Mediated Airway Remodeling

Frontiers in Immunology, 2018
Airway remodeling is responsible for the progressive decline of lung function in bronchial asthma. Matrix metalloproteinase-2 and fibroblast-to-myofibroblast transition are involved in tissue remodeling.
Yu Kuwabara, Tetsu Kobayashi, Corina N. D'Alessandro-Gabazza, Masaaki Toda, Taro Yasuma, Kota Nishihama, Atsuro Takeshita, Hajime Fujimoto, Mizuho Nagao, Takao Fujisawa, Esteban C. Gabazza   +10 more
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The extracellular matrix degradation markers as predictors of left ventricular systolic dysfunction among patients with STEMI

Сучасні медичні технології, 2021
The purpose of the study. To determine predictor value of the extracellular matrix degradation markers relative to the occurrence of left ventricular systolic dysfunction among patients with STEMI determined. Materials and methods.
I. M. Fushtey, E. V. Sid
doaj   +1 more source

Serum MMP-8 and TIMP-1 as prognostic biomarkers in gastric cancer

Tumor Biology, 2018
Despite gastric cancer being rare nowadays in Western countries, it remains one of the leading causes of cancer death worldwide. The course of the disease varies, so the individual gastric cancer patient’s prognosis is difficult to determine.
Alli Laitinen, Jaana Hagström, Harri Mustonen, Arto Kokkola, Taina Tervahartiala, Timo Sorsa, Camilla Böckelman, Caj Haglund   +7 more
doaj   +1 more source

Integrin α2β1 Expression Regulates Matrix Metalloproteinase-1-Dependent Bronchial Epithelial Repair in Pulmonary Tuberculosis

Frontiers in Immunology, 2018
Pulmonary tuberculosis (TB) is caused by inhalation of Mycobacterium tuberculosis, which damages the bronchial epithelial barrier to establish local infection.
Sara Brilha, Sara Brilha, Deborah L. W. Chong, Akif A. Khawaja, Catherine W. M. Ong, Catherine W. M. Ong, Naomi J. Guppy, Joanna C. Porter, Jon S. Friedland   +8 more
doaj   +1 more source

Correlation of matrix metalloproteinase 3 and matrix metalloproteinase 9 levels with non-motor symptoms in patients with Parkinson’s disease

Frontiers in Aging Neuroscience, 2022
ObjectiveMatrix metalloproteinases (MMPs) are essential for tissue formation, neuronal network remodeling, and blood–brain barrier integrity. MMPs have been widely studied in acute brain diseases.
Chuan Ze Liu, Chuan Ze Liu, Da Shuai Guo, Da Shuai Guo, Jian Jun Ma, Jian Jun Ma, Jian Jun Ma, Lin Rui Dong, Lin Rui Dong, Qing Qing Chang, Qing Qing Chang, Hong Qi Yang, Hong Qi Yang, Hong Qi Yang, Ke Ke Liang, Ke Ke Liang, Xiao Huan Li, Xiao Huan Li, Da Wei Yang, Da Wei Yang, Yong Yan Fan, Yong Yan Fan, Qi Gu, Qi Gu, Qi Gu, Si Yuan Chen, Si Yuan Chen, Si Yuan Chen, Dong Sheng Li, Dong Sheng Li, Dong Sheng Li   +30 more
doaj   +1 more source

Matrix metalloproteinases and epileptogenesis [PDF]

Molecular and Cellular Pediatrics, 2014
Matrix metalloproteinases are vital drivers of synaptic remodeling in health and disease. It is suggested that at early stages of epileptogenesis, inhibition of matrix metalloproteinases may help ameliorate cell death, aberrant network rewiring, and neuroinflammation and prevent development of epilepsy.
openaire   +2 more sources