Results 311 to 320 of about 2,395,043 (357)

Emerging Nanozyme Strategies for Precision Breast Cancer Treatment

Advanced Science, EarlyView.
Different types of nanozymes‐mediated chemotherapy, photothermal therapy, immunotherapy, and multiple combined therapies for the effective treatment of breast cancer. Abstract Breast cancer, the most common malignant tumor among women worldwide, poses a significant challenge to public health due to its high incidence and mortality rates.
Jian Zang, Zhaozhou Ren, Haibo Wang, Xing Yang, Yang Song, Jun Liao, Xiaoying Li   +6 more
wiley   +1 more source

Matrix metalloproteinase-7 is dispensable in a mouse model of sepsis-induced acute lung injury. [PDF]

PLoS One
Baer B, Lin J, Schaaf KR, Ware LB, Shaver CM, Bastarache JA.   +5 more
europepmc   +1 more source

Antioxidant Carbon Dot of Selenomethionine Alleviates Oxidative Stress in Intervertebral Disc Degeneration

Advanced Science, EarlyView.
A selenomethionine‐derived carbon dot (Se‐Met‐CD) serves as a potent nano‐antioxidant, efficiently scavenging reactive oxygen species, protecting nucleus pulposus cells from oxidative damage, restoring extracellular matrix homeostasis, and significantly mitigating intervertebral disc degeneration in vivo, which demonstrates great promise as a nanozyme ...
Qingzheng Zhang, Zongtai Liu, Yirong Sun, Changfeng Fu, Jianxun Ding   +4 more
wiley   +1 more source

Applications of Matrix Metalloproteinase-9-Related Nanomedicines in Tumors and Vascular Diseases. [PDF]

Pharmaceutics
Li X, Xu Z.
europepmc   +1 more source

Nanoscopic Mapping of the Extracellular Space in Amyloid Plaque‐rich Cortex

Advanced Science, EarlyView.
The extracellular space and diffusion around amyloid plaques are examined using shadow imaging and single‐particle tracking. Increased diffusivity is found near plaques, extracellular matrix alterations, and plaque core penetrability that varies with amyloid phenotype.
Juan Estaún‐Panzano, Yulia Dembitskaya, Ivo Calaresu, Somen Nandi, Quentin Gresil, Evelyne Doudnikoff, Thierry Leste‐Laserre, Thierry Amédée, Laurent Cognet, Laurent Groc, Urs Valentin Nägerl, Erwan Bezard   +11 more
wiley   +1 more source

Deciphering the oncogenic influence of Pasteurella multocida: Implications of matrix metalloproteinase activation. [PDF]

Heliyon
Nambiar J, Venugopal M, Shaji SK, Bose C, Rajeev A, Kalliadan S, Haripriyan J, Nair BG.   +7 more
europepmc   +1 more source

The Mechanism and Potential Therapeutic Strategies of Vascular Aging

AGING MEDICINE, EarlyView.
The phenotypes of vascular aging vary across different blood vessels. Endothelial dysfunction is observable in the endothelium of all vessels, while vascular structural remodeling primarily occurs in arteries. A decline in organ vascular density mainly affects arterioles, venules, and capillaries, whereas thrombosis predominantly occurs in the ...
Wan‐Zhou Wu, Xuan Wang, Fang‐Fang Wu, Xiao‐Tian Yan, Yong‐Ping Bai   +4 more
wiley   +1 more source

IGF-1 downregulates matrix metalloproteinase 8 to promote plaque stability: Evidence from myeloid cell-specific MMP8 in atherosclerosis. [PDF]

PLoS One
Snarski P, Sukhanov S, Yoshida T, Danchuk S, Gross A, Sindi F, Rivera-Lopez V, Delafontaine P, Higashi Y.   +8 more
europepmc   +1 more source

Visualization of OPN‐Targeted Self‐Assembled Micelles Encapsulated With an SIRT6 Activator and Doped Indocyanine Green for Attenuating Vascular Aging

AGING MEDICINE, EarlyView.
We developed a visualized OPN‐targeted nanodelivery system loaded with MDL800 and ICG to attenuate vascular aging via activating SIRT6 to reduce MMP9 in a mice model, providing a promising anti‐aging strategy for future clinical applications. ABSTRACT Objectives Sirtuin 6 (SIRT6) is a longevity‐associated gene with recognized therapeutic potential for ...
Yan Fang, Wenyue Li, Cheng Qin, Mengqi Xu, Naiyuan Sun, Tingting Lu, Zhiyi Fang, Yan Ma, Linghuan Wang, Sulei Li, Xiaojing Wan, Hui Li, Renzheng Chen, Xiaoying Shen, Lei Tian, Jing Liu, Yi Hou, Feng Cao   +17 more
wiley   +1 more source

Interleukin-37 reduces lipopolysaccharide induced matrix metalloproteinase-9 in gingival epithelial cells. [PDF]

BMC Oral Health
Beklen A, Yavuz MB, Uckan D.
europepmc   +1 more source