Results 31 to 40 of about 2,335,867 (359)

Matrix Metalloproteinase in Abdominal Aortic Aneurysm and Aortic Dissection

open access: yesPharmaceuticals, 2019
Abdominal Aortic Aneurysm (AAA) affects 4–5% of men over 65, and Aortic Dissection (AD) is a life-threatening aortic pathology associated with high morbidity and mortality.
E. M. Maguire   +4 more
semanticscholar   +1 more source

Serum MMP-8 and TIMP-1 as prognostic biomarkers in gastric cancer

open access: yesTumor Biology, 2018
Despite gastric cancer being rare nowadays in Western countries, it remains one of the leading causes of cancer death worldwide. The course of the disease varies, so the individual gastric cancer patient’s prognosis is difficult to determine.
Alli Laitinen   +7 more
doaj   +1 more source

A Hybrid Model of a Genetic Regulatory Network in Mammalian Sclera [PDF]

open access: yesEPTCS 125, 2013, pp. 99-105, 2013
Myopia in human and animals is caused by the axial elongation of the eye and is closely linked to the thinning of the sclera which supports the eye tissue. This thinning has been correlated with the overproduction of matrix metalloproteinase (MMP-2), an enzyme that degrades the collagen structure of the sclera.
arxiv   +1 more source

Integrin α2β1 Expression Regulates Matrix Metalloproteinase-1-Dependent Bronchial Epithelial Repair in Pulmonary Tuberculosis

open access: yesFrontiers in Immunology, 2018
Pulmonary tuberculosis (TB) is caused by inhalation of Mycobacterium tuberculosis, which damages the bronchial epithelial barrier to establish local infection.
Sara Brilha   +8 more
doaj   +1 more source

The extracellular matrix degradation markers as predictors of left ventricular systolic dysfunction among patients with STEMI

open access: yesСучасні медичні технології, 2021
The purpose of the study. To determine predictor value of the extracellular matrix degradation markers relative to the occurrence of left ventricular systolic dysfunction among patients with STEMI determined. Materials and methods.
I. M. Fushtey, E. V. Sid
doaj   +1 more source

Matrix metalloproteinases as new targets in Alzheimer's disease: Opportunities and Challenges [PDF]

open access: yesJournal of Medicinal Chemistry, American Chemical Society, 2020, 2021
Although matrix metalloproteinases (MMPs) are implicated in the regulation of numerous physiological processes, evidences of their pathological roles have also been obtained in the last decades, making MMPs attractive therapeutic targets for several diseases.
arxiv  

An injectable, self-healing and MMP-inhibiting hyaluronic acid gel via iron coordination [PDF]

open access: yes, 2021
Regulating the activity of matrix metalloproteinases (MMPs) is a potential strategy for osteoarthritis (OA) therapy, although delivering this effect in a spatially and temporally localised fashion remains a challenge. Here, we report an injectable and self-healing hydrogel enabling factor-free MMP regulation and biomechanical competence in situ.
arxiv   +1 more source

Matrix metalloproteinase-9 as an independent predictor of recurrence after catheter ablation of atrial fibrillation

open access: yesJournal of Education, Health and Sport, 2017
Objectives: In this study, the serum level of matrix metalloproteinase-9 was studied as an independent predictor of recurrence after catheter ablation of a persistent form of atrial fibrillation. Methods: The study included 46 patients with a persistent
A. V. Goryachiy   +5 more
doaj   +3 more sources

Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-beta and promotes tumor invasion and angiogenesis.

open access: yesGenes & Development, 2000
We have uncovered a novel functional relationship between the hyaluronan receptor CD44, the matrix metalloproteinase-9 (MMP-9) and the multifunctional cytokine TGF-beta in the control of tumor-associated tissue remodeling.
Q. Yu, I. Stamenkovic
semanticscholar   +1 more source

Matrix metalloproteinase 9 level as an indicator for restenosis following cervical and intracranial angioplasty and stenting

open access: yesNeural Regeneration Research, 2015
Cervical and intracranial angioplasty and stenting is an effective and safe method of reducing the risk of ischemic stroke, but it may be affected by in-stent restenosis.
Jun-peng Liu   +4 more
doaj   +1 more source

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