Results 31 to 40 of about 2,395,043 (357)
Protective Role of Matrix Metalloproteinase-2 in Allergic Bronchial Asthma
Frontiers in Immunology, 2019 Inflammation, reversible obstruction, and hyperresponsiveness of the airways are characteristic findings of bronchial asthma. Several evidence has demonstrated the involvement of matrix metalloproteinase-2 in allergic airway inflammation.
Yoshinori Takahashi +17 more
doaj +1 more source
Leptin and Pro-Inflammatory Stimuli Synergistically Upregulate MMP-1 and MMP-3 Secretion in Human Gingival Fibroblasts. [PDF]
PLoS ONE, 2016 Gingival fibroblast-mediated extracellular matrix remodelling is implicated in the pathogenesis of periodontitis, yet the stimuli that regulate this response are not fully understood.
Rachel C Williams +5 more
doaj +1 more source
Клінічна хірургія, 2022 Objective. To improve the results of treatment in patients, suffering insufficiency of sutures of intestinal anastomoses, using analysis of rate in the genes polymorphous variants of the matrix metalloproteinase Type 2 (C-1306 →T) and the tissue ...
O. Yu. Usenko, Ya. Yu. Voitiv
doaj +1 more source
The Rebirth of Matrix Metalloproteinase Inhibitors: Moving Beyond the Dogma
Cells, 2019 The pursuit of matrix metalloproteinase (MMP) inhibitors began in earnest over three decades ago. Initial clinical trials were disappointing, resulting in a negative view of MMPs as therapeutic targets.
G. Fields
semanticscholar +1 more source
Matrix Metalloproteinase-9 (MMP-9) as a Cancer Biomarker and MMP-9 Biosensors: Recent Advances
Italian National Conference on Sensors, 2018 As one of the most widely investigated matrix metalloproteinases (MMPs), MMP-9 is a significant protease which plays vital roles in many biological processes. MMP-9 can cleave many extracellular matrix (ECM) proteins to regulate ECM remodeling.
Hao-Hsiu Huang
semanticscholar +1 more source
Inhibition of Trophoblast-Induced Spiral Artery Remodeling Reduces Placental Perfusion in Rat Pregnancy. [PDF]
, 2010 Rats harboring the human angiotensinogen and human renin genes develop preeclamptic features in pregnancy. The preeclamptic rats exhibit a deeper trophoblast invasion associated with a reduced resistance index by uterine Doppler.
Cartwright, JE +12 more
core +1 more source
Cell Transplantation, 2019 Emerging evidence demonstrates that dysregulation of circular RNA is linked to tumorigenesis and aggressive progression. However, its role in oral squamous cell carcinoma remains largely uncharacterized.
Bing Xia +4 more
doaj +1 more source
Role of Matrix Metalloproteinase-2 in Eosinophil-Mediated Airway Remodeling
Frontiers in Immunology, 2018 Airway remodeling is responsible for the progressive decline of lung function in bronchial asthma. Matrix metalloproteinase-2 and fibroblast-to-myofibroblast transition are involved in tissue remodeling.
Yu Kuwabara +10 more
doaj +1 more source
Matrix Metalloproteinase in Abdominal Aortic Aneurysm and Aortic Dissection
Pharmaceuticals, 2019 Abdominal Aortic Aneurysm (AAA) affects 4–5% of men over 65, and Aortic Dissection (AD) is a life-threatening aortic pathology associated with high morbidity and mortality.
E. M. Maguire +4 more
semanticscholar +1 more source
Serum MMP-8 and TIMP-1 as prognostic biomarkers in gastric cancer
Tumor Biology, 2018 Despite gastric cancer being rare nowadays in Western countries, it remains one of the leading causes of cancer death worldwide. The course of the disease varies, so the individual gastric cancer patient’s prognosis is difficult to determine.
Alli Laitinen +7 more
doaj +1 more source