Results 291 to 300 of about 700,477 (342)

Matrix metalloproteinase-9 and matrix metalloproteinase-2 gene polymorphisms in multiple sclerosis

Journal of Neuroimmunology, 2008
We investigated the association of matrix metalloproteinase-9 (-1562C/T, +279R/Q) and matrix metalloproteinase-2 (-1575G/A, -1306C/T) gene polymorphisms with multiple sclerosis (MS) susceptibility, gender differences and disability in 244 patients and 132 healthy subjects.
Yvonne, Benesová, Anna, Vasků, Pavel, Stourac, Magdalena, Hladíková, Michal, Beránek, Zdenek, Kadanka, Hana, Novotná, Josef, Bednarík   +7 more
openaire   +2 more sources

Matrix metalloproteinase-2 and Matrix metalloproteinase-9 in cholesteatoma and deep meatal skin

Clinical Otolaryngology and Allied Sciences, 1998
A qualitative and quantitative study of the presence of Matrix metalloproteinase-2 (MMP-2) and Matrix metalloproteinase-9 (MMP-9) in cholesteatoma was performed. Ten cholesteatoma and four deep meatal skin specimens were analysed for gelatinase activity at molecular weights corresponding to MMP-2 and MMP-9 using Sodium Dodecyl Sulphate Polyacrylamide ...
A R, Banerjee, R, James, A A, Narula
openaire   +2 more sources

Increased Expression of Matrix Metalloproteinase-2, Matrix Metalloproteinase-9 and Matrix Metalloproteinase-13 in Lesional Skin of Bullous Pemphigoid

International Archives of Allergy and Immunology, 2006
<i>Background:</i> Matrix metalloproteinase (MMP)-2, MMP-9 and MMP-13 can degrade type IV collagen which is the major component of the basement membrane zone (BMZ). In bullous pemphigoid (BP), the separation occurs within the BMZ. <i>Objective:</i> To evaluate the involvement of MMPs in the pathogenesis of BP, we examined the ...
Yayoi, Niimi, Ruby, Pawankar, Seiji, Kawana   +2 more
openaire   +2 more sources

Membrane-type matrix metalloproteinases: membrane-type 1 matrix metalloproteinase, membrane-type 2 matrix metalloproteinase and membrane-type 3 matrix metalloproteinase in endometriosis and adenomyosis

2023
Endometriosis is a benign gynecological disease characterized by the presence of endometrial tissue; endometrial glands and stroma outside the uterus. Even though endometriosis affects about 0.7-8.6% women of the reproductive age, the pathogenesis is not well understood and there is no reliable non-invasive biomarker for diagnosis.
Maoga, Jane Bosibori, Justus Liebig University Giessen   +1 more
openaire   +2 more sources

Neutrophil activator of matrix metalloproteinase-2 (NAM)

Clinical & Experimental Metastasis, 2006
We have isolated a novel soluble factor(s), neutrophil activator of matrix metalloproteinases (NAM), secreted by unstimulated normal human peripheral blood neutrophils that causes the activation of cell secreted promatrix metalloproteinase-2 (proMMP-2).
Ellen E, Rollo, Michelle, Hymowitz, Cathleen E, Schmidt, Steve, Montana, Hussein, Foda, Stanley, Zucker   +5 more
openaire   +2 more sources

Matrix metalloproteinase-2 promoter variability in psoriasis

Archives of Dermatological Research, 2009
The expression of matrix metalloproteinase-2 was observed to be significantly upregulated in psoriasis. The aim of this study was to associate the DNA polymorphic variants in MMP-2 promoter gene with psoriasis and/or with psoriasis phenotypes related to psoriasis and comorbid heredity.
Vladimir, Vasku, Julie, Bienertova Vasku, Veronika, Slonková, Katerina, Kanková, Anna, Vasku   +4 more
openaire   +2 more sources

Matrix metalloproteinase-2, membranous type 1 matrix metalloproteinase, and tissue inhibitor of metalloproteinase-2 expression in ectopic and eutopic endometrium

Fertility and Sterility, 2002
To investigate expression of matrix metalloproteinase-2 (MMP-2), membranous type 1 matrix metalloproteinase (MT1-MMP), and tissue inhibitor of metalloproteinase-2 (TIMP-2) in ectopic and eutopic endometrium from women with and without endometriosis throughout the menstrual cycle.Molecular studies in human tissue.Reproductive immunology laboratory of a ...
Hye Won, Chung, Ji Young, Lee, Hye-Sung, Moon, Sung Eun, Hur, Mi Hye, Park, Yan, Wen, Mary Lake, Polan   +6 more
openaire   +2 more sources

Whole Blood Assay for Elastase, Chymotrypsin, Matrix Metalloproteinase-2, and Matrix Metalloproteinase-9 Activity

Analytical Chemistry, 2010
The ability to measure protease activity in the blood is important for the development of future diagnostics and for biomedical research. Presently, protease assays require sample preparation, making them time-consuming, costly, less accurate, and unsuitable for point-of-care (POC) diagnostics.
Roy B, Lefkowitz, Geert W, Schmid-Schönbein, Michael J, Heller   +2 more
openaire   +2 more sources

Expression of cyclooxygenase-2, matrix metalloproteinase-2 and matrix metalloproteinase-9 in premenopausal and postmenopausal endometrial polyps

Maturitas, 2008
Cyclooxygenase-2 (COX-2) and matrix metalloproteinase-2 and -9 (MMP-2 and MMP-9) are influenced by relative levels of estrogen and are involved in promoting cell proliferation and angiogenesis. The present study investigated expression of COX-2, MMP-2 and MMP-9 in endometrial polyps from premenopausal and postmenopausal women.Premenopausal (n=18) and ...
GÜNEY, Mehmet, ERDEMOĞLU, Evrim, Mungan, Tamer, KARAHAN, Nermin   +3 more
openaire   +4 more sources

Fibrillin-2 Degradation by Matrix Metalloproteinase-2 in Periodontium

Journal of Dental Research, 2007
Elastic system fibers, comprised of microfibrils and tropoelastin, are extracellular components of periodontal tissue. During development, the microfibrils act as a template on which tropoelastin is deposited. However, the process of elastic system fiber remodeling is not fully understood. Therefore, we examined whether matrix metalloproteinases (MMPs)
E, Tsuruga, K, Irie, T, Yajima
openaire   +2 more sources