Journal of Biological Chemistry, 1992 Matrix metalloproteinase 9 (MMP-9), also known as 92-kDa gelatinase/type IV collagenase, is secreted from neutrophils, macrophages, and a number of transformed cells in zymogen form. Here we report that matrix metalloproteinase 3 (MMP-3/stromelysin) is an activator of the precursor of matrix metalloproteinase 9 (proMMP-9).
Ogata, Y, Enghild, J J, Nagase, H
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Inhibition of interleukin-1β-stimulated collagenase and stromelysin expression in human tendon fibroblasts by epigallocatechin gallate ester [PDF]
, 2004 The medicinal benefits of green tea (Camellia sinensis) consumption have been attributed to bioavailable polyphenols, notably epigallocatechin gallate (EGCG).
Buttle, David J. +4 more
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Matrix metalloproteinase-9 is up-regulated by CCL21/CCR7 interaction via extracellular signal-regulated kinase-1/2 signaling and is involved in CCL21-driven B-cell chronic lymphocytic leukemia cell invasion and migration [PDF]
, 2007 4 páginas, 2 figuras -- PAGS nros. 383-386B-cell chronic lymphocytic leukemia (B-CLL) progression is frequently accompanied by clinical lymphadenopathy, and the CCL21 chemokine may play an important role in this process. Indeed, CCR7 (the CCL21 receptor),
Javier Redondo-Muñoz +9 more
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Biotechnic & Histochemistry, 2017 Matrix metalloproteases (MMPs) are endogenous proteases that are responsible for degradation of extracellular matrix (ECM) proteins and cell surface antigens. The breakdown of ECM participates in the local invasion and distant metastases of malignant tumors.
A Akkoc, D Nak, A Demirer, G Şimşek
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The role of matrix metalloproteinase 9 in immune-mediated skin diseases
Frontiers in ImmunologyMMP-9, dependent on zinc, is a key endopeptidase involved in tissue homeostasis, inflammation, and immune-related pathological processes through its role in extracellular matrix degradation and remodeling.
Ke Xu +10 more
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Tumor Epithelial Cell Matrix Metalloproteinase 9 (MMP-9) is a Prognostic Marker in Colorectal Cancer [PDF]
, 2008 Presented at American Association Cancer Research in 2008 Zuzga D.S., Gibbons A.V., Li P., Lubbe W.J., Chervoneva I., Pitari G.M. “Tumor epithelial cell MMP-9 is a prognostic marker in colorectal cancer”.
AV Gibbons, +5 more
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Immunohistochemical Expression of Matrix Metalloprotease-2 and Matrix Metalloprotease-9 in the Disks of Patients with Temporomandibular Joint Dysfunction [PDF]
, 2015 Purpose Matrix metalloproteases (MMPs) are tissue-remodeling enzymes that function during the remodeling process, such as in immune-inflammatory diseases.
Almeida, Luis Eduardo +6 more
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Matrix metalloproteinase-9 regulates graft bone resorption.
The Angle orthodontist, 2006 Objective: To explore the relationship between bone resorption and matrix metalloproteinase-9 (MMP-9) expression in autogenous and allogenic bone grafts. Materials and Methods: A total of 18 critical-size (10 x 15 mm) defects were created in rabbit mandibles bilaterally.
Rabie, ABM, Lu, M
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Increased Serum Activity of Matrix Metalloproteinase-9 in Patients with Acute Variceal Bleeding
Gut and Liver, 2012 Background/AimsMatrix metalloproteinases (MMP)-2 and -9 can degrade essential components of vascular integrity. The aim of this study was to investigate the association between those MMPs and variceal bleeding (VB).Methods : Fifteen controls, 12 patients
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