Results 111 to 120 of about 248,248 (311)

The Effects of Channa Striatus Extract Administration on Wound Healing Markers (il-6, Mmp-9 and Vegf) in Post Lower Segment Caesarean Section (lscs) Women [PDF]

, 2016
Channa Striatus (Haruan) digunakan secara meluas di Malaysia untuk menggalakkan penyembuhan luka. Sejak turun temurun, C.striatus telah dipercayai mempunyai sifat anti-radang, anti-oksida dan anti sakit untuk penyembuhan luka yang lebih baik ...
Zainan, Ahmad Ezam
core  

Hypoxia increases neutrophil-driven matrix destruction after exposure to Mycobacterium tuberculosis. [PDF]

, 2018
The importance of neutrophils in the pathology of tuberculosis (TB) has been recently established. We demonstrated that TB lesions in man are hypoxic, but how neutrophils in hypoxia influence lung tissue damage is unknown.
A Dorhoi, A Mantovani, AM Houghton, AM McInturff, C Peyssonnaux, CW Ong, CW Ong, D Nickel, J Rius, JE Galagan, JM McCracken, K Dheda, K Ostridge, K Steinwede, LW Garratt, M Datta, MP Berry, N Borregaard, N Branzk, NN McGovern, PM Elks, PM Elks, PT Elkington, PT Elkington, PT Elkington, PT Elkington, S Aliberti, SC Cheng, SH Kaufmann, SH Oehlers, SR Walmsley, SS Shell, ST Reece, SY Eum, TA Fuchs, V Nizet, V Ramos-Kichik   +36 more
core   +1 more source

Bioengineered Pancreatic Cancer Immunosuppressive Microenvironment Models for Screening Immunotherapies

Advanced Healthcare Materials, EarlyView.
Bioengineering tumor‐stroma pancreatic cancer models with potential to emulate the native immunosuppressive tumor microenvironment. Cancer‐on‐a‐bead models exhibited higher relevance for screening immunotherapies and modulating the protumoral PDAC microenvironment. ABSTRACT Pancreatic cancer is notably resistant to treatment, primarily due to its dense
Maria V. Monteiro, Margarida Henriques‐Pereira, Bruno M. Neves, Vítor M. Gaspar, João F. Mano   +4 more
wiley   +1 more source

Eotaxin-induced expression of membrane type 1 matrix metalloproteinase mRNA in human eosinophils

Allergology International, 2000
Eosinophil penetration across the basement membrane (BM) is thought to be dependent on the degradation of membrane components. In this process, matrix metalloproteinases (MMP) appear to be primarily responsible for degradation of the BM.
Izumi Kurosaki, Taku Satoh, Koji Murakami, Takeshi Tastumi, Noriyasu Mitani, Ikuo Saiki   +5 more
doaj   +1 more source

Spherical Skin Model: Stratified Co‐Culture of Fibroblasts and Keratinocytes on Spherical Beads Toward Compound Screening

Advanced Healthcare Materials, EarlyView.
Models of the human skin must combine the relevant biological contents and suitable biomaterials with the correct spatial organization. Performing compound screening on such in vitro models also requires fast and reproducible production methods of the models.
Elisa Lenzi, Nadia Vertti‐Quintero, Julien Husson, Anne‐Laure Bulteau, Carine Nizard, Karl Pays, Sébastien Sart, Charles N. Baroud   +7 more
wiley   +1 more source

Temporal and spatial expression of tissue inhibitors of metalloproteinases 1 and 2 (TIMP-1 and -2) in the bovine corpus luteum [PDF]

, 2003
The matrix metalloproteinases (MMPs) and their endogenous inhibitors, tissue inhibitors of metalloproteinases (TIMPs), may mediate the dramatic structural and functional changes in the corpus luteum (CL) over the course of its life span.
Moses, Marsha A., Tsang, Paul C.W., Zhang, Bo   +2 more
core   +3 more sources

Bioengineered Lymphatic Vessels in Synthetic Matrices to Study Breast Cancer Cell Functions

Advanced Healthcare Materials, EarlyView.
Lymphatic vessels are involved in cancer metastasis. To study the interplay between metastasizing cancer cells and lymphatic vessels under highly reproducible conditions, advanced in vitro models are required. In this work, 3D lymphatic networks are formed in biomimetic hydrogels and their interactions with invasive and non‐invasive cancer cell‐lines ...
Rodi Odabasi, Lisa A. Krattiger, Magdalini Kanari, Mira A. Jacobs, Lukas O. Moser, Mark W. Tibbitt, Cornelia Halin, Martin Ehrbar   +7 more
wiley   +1 more source

Enhanced cardiac expression of two isoforms of matrix metalloproteinase-2 in experimental diabetes mellitus. [PDF]

, 2019
BackgroundDiabetic cardiomyopathy (DM CMP) is defined as cardiomyocyte damage and ventricular dysfunction directly associated with diabetes independent of concomitant coronary artery disease or hypertension.
Ahn, Jinhee, Bae, Sun Sik, Cha, Kwang Soo, Choi, Jung Hyun, Hong, Taek Jong, Kim, Sang Sik, Lee, Han Cheol, Lee, Hye Won, Lee, Min Young, Lee, Sun Ju, Lovett, David H, Oh, Jun-Hyok, Park, Jin-Sup, Park, Mi Wha, Shin, Nari, Song, Sang Heon   +15 more
core   +2 more sources

New Insights into Atonic Postpartum Hemorrhage: Animal Model Construction Based on Placental Nanodelivery Systems

Advanced Healthcare Materials, EarlyView.
This study develops a placenta‐targeted nanodelivery system co‐loading HMGB1 protein and the NLRP3 agonist nigericin to establish an animal model of atonic postpartum hemorrhage. The model accurately recapitulates clinical phenotypes, including prolonged labor and uterine contractility dysfunction, while revealing inflammatory activation in placental ...
Jiangxue Qu, Ruiqi Wu, Hai Jiang, Lian Chen, Yingying Tian, Shuai Zeng, Tongmin Liu, Cheng Zhao, Huifeng Shi, Xiaolong Liang, Yangyu Zhao   +10 more
wiley   +1 more source

Investigating salivary matrix metalloproteinase-2 and matrix metalloproteinase-9 activity in fixed orthodontic-induced gingival enlargement

Dental Research Journal
Background: Gingival enlargement (GE) is a common clinical observation among orthodontic patients, yet its underlying causes remain unclear. This study aims to investigate the potential involvement of salivary matrix metalloproteinase (MMP)-2 and MMP-9 ...
Narges Ziaei, Amir Kiani, Ehsan Mohammadi-Noori, Shahram Arishi, Shima Golmohammadi   +4 more
doaj   +1 more source