Results 191 to 200 of about 248,248 (311)

CRISPLD2 Attenuates Intervertebral Disc Degeneration by Suppressing Oxidative Stress‐Induced Ferroptosis through the miR‐548I‐IL17A Axis

Advanced Science, EarlyView.
This study identifies CRISPLD2 as a key protector against IVDD. By regulating ferroptosis through the CRISPLD2–miR‐548I–IL17A axis, CRISPLD2 maintains NPCs homeostasis and reduces oxidative stress. Restoring CRISPLD2 expression effectively alleviates disc degeneration and highlights a promising therapeutic strategy for discogenic low back pain ...
Yangyang Shi, Fudong Li, Tianyi Zhao, Kaiqiang Sun, Danying Zhang, Chen Yan, Ximing Xu, Jingchuang Sun, Xulin Hu, Xin Yong, Jiangang Shi, Yuan Wang   +11 more
wiley   +1 more source

Targeting Matrix Metalloproteinase-9 to Alleviate T Cell Exhaustion and Improve Sepsis Prognosis. [PDF]

Research (Wash D C)
Wang X, Ning J, Zhou L, Li H, Cui J, Wang J, Liang X, Li J, Li M, Gao X, Li W, Chen X, Yu F, Wei L, Ma C.   +14 more
europepmc   +1 more source

Role of Matrix Metalloproteinase (MMP) 2 and MMP-9 in Soft Tissue Sarcoma

, 2014
Hyun Kee Yang, Kwang Cheul Jeong, Yang Kyung Kim, Sung Taek Jung   +3 more
openalex   +1 more source

The Fragile X Mental Retardation Protein Regulates Matrix Metalloproteinase 9 mRNA at Synapses [PDF]

, 2013
Aleksandra Janusz, Jacek Miłek, Małgorzata Perycz, Laura Pacini, Claudia Bagni, Leszek Kaczmarek, Magdalena Dziembowska   +6 more
openalex   +1 more source

CD147/Basigin: From Integrative Molecular Hub to Translational Therapeutic Target

Advanced Science, EarlyView.
This review conceptualizes CD147 as a fundamental “Energy‐Structure Coupler,” physically bridging metabolic flux (via MCTs) with morphogenetic plasticity (via integrins/MMPs) to drive cancer, infection, and autoimmunity. Addressing the “specificity paradox” that limits current translation, the authors chart a strategic roadmap—spanning logic‐gated ...
Xiang‐Min Yang, Huijie Bian, Zhi‐Nan Chen   +2 more
wiley   +1 more source

Comparison of Serum Matrix Metalloproteinase-9 Levels in Diabetic and Non-diabetic Chronic Wounds. [PDF]

Cureus
Joseph J, Chandranaath A, Louis J, Rubby SA, Govindan VK, Veronika M.   +5 more
europepmc   +1 more source

Supplementary Data from Associations of Matrix Metalloproteinase-9 Protein Polymorphisms with Lymph Node Metastasis but not Invasion of Gastric Cancer

, 2023
Yang Tang, Jinwei Zhu, Ling Chen, Linyin Chen, Sheng Zhang, Jianyin Lin   +5 more
openalex   +1 more source

Trojan Horse Strategy: How Biomimetic Nanomedicine Remodels the Tumor Microenvironment

Advanced Science, EarlyView.
This review focuses on biomimetic nanomedicines for tumor microenvironment (TME) remodeling, covering their diverse biomimetic types, design principles, and mechanisms of immune cell reprogramming and reversal of immunosuppressive microenvironments, with particular emphasis on their application in synergistic immunotherapy.
Wanrong Wang, Siqi Mu, Juan Zhang, Guisong Shan, Xueqian Li, Ran Wang, Tao Guo, Xiaoyan He   +7 more
wiley   +1 more source

Matrix Metalloproteinase-9 (MMP-9) as a Therapeutic Target: Insights into Molecular Pathways and Clinical Applications. [PDF]

Pharmaceutics
Wolosowicz M, Prokopiuk S, Kaminski TW.
europepmc   +1 more source

Effect of Continuous Endurance Training on mRNA Expression of Interferon Gamma and Matrix Metalloproteinase-9 in Male Elder Rats

, 2018
Elham Mousavi, Mohammad Reza Asad, Ali Barzegari, Mahbobeh Gholizadeh ahangari   +3 more
openalex   +2 more sources