Results 101 to 110 of about 9,265,306 (307)

Demography of marine birds in the Northeast Atlantic: Informed parameter values for population modelling

Ecological Solutions and Evidence
Matrix models are often used to assess and predict the impact of human activities on wild populations. These models require input values of demographic parameters, that is survival and fecundity. However, empirical estimates of these parameters are often
Morten Frederiksen, Tycho Anker‐Nilssen, Thomas Bregnballe, Volker Dierschke, Svein‐Håkon Lorentsen, Ian Mitchell, Matt Parsons, Hans Schekkerman, Eric Stienen, Hallvard Strøm   +9 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Generalized admittance matrix models of OTRAs and COAs

, 2010
This paper proposes new admittance matrix models to approach the behavior of fully-differential Operational Transresistance Amplifiers (OTRAs) and Current Operational Amplifiers (COAs).
ESTEBAN TLELO CUAUTLE, CARLOS SANCHEZ LOPEZ   +1 more
core  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Empirical Transition Matrix of Multi-State Models: The etm Package [PDF]

Multi-State models provide a relevant framework for modelling complex event histories. Quantities of interest are the transition probabilities that can be estimated by the empirical transition matrix, that is also referred to as the Aalen-Johansen ...
Martin Schumacher, Jan Beyersmann, Arthur Allignol   +2 more
core  

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Bayesian Estimation of A Distance Functional Weight Matrix Model [PDF]

This paper considers the distance functional weight matrix in spatial autoregressive and spatial error models from a Bayesian point of view. We considered the Markov chain Monte Carlo methods to estimate the parameters of the models.
Kazuhiko Kakamu
core  

Perturbed generalized multicritical one-matrix models

Nuclear Physics B, 2018
We study perturbations around the generalized Kazakov multicritical one-matrix model. The multicritical matrix model has a potential where the coefficients of zn only fall off as a power 1/ns+1.
J. Ambjørn, L. Chekhov, Y. Makeenko
doaj   +1 more source

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

FEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual, Marta Navarro‐Gutiérrez, Verónica Romero‐Albillo, Raquel Jiménez‐Sánchez   +3 more
wiley   +1 more source