Results 111 to 120 of about 3,541,835 (287)
Small M-theories unify various models of a given family in the same way as the M-theory unifies a variety of superstring models. We consider this idea in application to the family of eigenvalue matrix models: their M-theory unifies various branches of ...
A. Alexandrov +35 more
core +1 more source
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Conceptual frameworks of barriers and facilitators to perinatal mental healthcare: the MATRIx models. [PDF]
Webb R +8 more
europepmc +1 more source
Glassy random matrix models [PDF]
This paper discusses Random Matrix Models which exhibit the unusual phenomena of having multiple solutions at the same point in phase space. These matrix models have gaps in their spectrum or density of eigenvalues. The free energy and certain correlation functions of these models show differences for the different solutions.
openaire +3 more sources
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Topological order in matrix Ising models
We study a family of models for an $N_1 \times N_2$ matrix worth of Ising spins $S_{aB}$. In the large $N_i$ limit we show that the spins soften, so that the partition function is described by a bosonic matrix integral with a single `spherical ...
Sean A. Hartnoll, Edward A. Mazenc, Zhengyan D. Shi
doaj +1 more source
Fibroblast-derived matrix models desmoplastic properties and forms a prognostic signature in cancer progression. [PDF]
Rafaeva M +16 more
europepmc +1 more source
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Personalized in vitro Extracellular Matrix Models of Collagen VI-Related Muscular Dystrophies. [PDF]
Almici E +12 more
europepmc +1 more source

