Results 111 to 120 of about 665,812 (269)
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
FEBS Open Bio, EarlyView.PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
Efficient higher-order matrix product operators for time evolution
SciPost PhysicsWe introduce a systematic construction of higher-order matrix product operator (MPO) approximations of the time evolution operator for generic (short and long range) one-dimensional Hamiltonians. We demonstrate the utility of our construction, by showing
Maarten Van Damme, Jutho Haegeman, Ian McCulloch, Laurens Vanderstraeten
doaj +1 more source
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
FEBS Open Bio, EarlyView.Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
SignalsToeplitz matrix–vector products are used in many digital signal processing applications. Direct methods for calculating such products require N2 multiplications and N(N−1) additions, where N denotes the order of the Toeplitz matrix.
Janusz P. Papliński +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
Measurement-induced phase transitions by matrix product states scaling
Physical Review ResearchWe study the time evolution of long quantum spin chains subjected to continuous monitoring projected on matrix product states (MPS) with fixed bond dimension, by means of the Time-Dependent Variational Principle (TDVP) algorithm.
Guillaume Cecile +2 more
doaj +1 more source
A family of 512 reverse order laws for generalized inverses of a matrix product: A review. [PDF]
Heliyon, 2020 Tian Y.
europepmc +1 more source
FEBS Open Bio, EarlyView.Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
FEBS Open Bio, EarlyView.MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source
On an inequality related to the volume of a parallelepiped
Examples and CounterexamplesThe problem of establishing an upper bound for the volume of a parallelepiped is considered by utilizing an original approach involving a skew-symmetric matrix of order four (along with its Moore–Penrose inverse).
Oskar Maria Baksalary, Götz Trenkler
doaj +1 more source